Al Khathami Abdulmajeed, Baklola Mohamed, Alshehri Anwar Ali, Alnasser Lujain Hussain, Alshehri Razan Saleh, Salawi Mohammed A, Alwadai Rahaf Hussain, Al Ghazwi Mohammed, Alanazi Amira Ahmed Qadim, Alshammari Asayel Mojidea, Al-Bawah Naji, Hafez Mayas, Abu Melha Abdullah
Department of Ophthalmology, King Fahad Hospital, Al Baha Health Cluster, Al Baha, Saudi Arabia.
Faculty of Medicine, Mansour University, Mansoura, Egypt.
Clin Ophthalmol. 2025 Jul 5;19:2117-2132. doi: 10.2147/OPTH.S539808. eCollection 2025.
Refractive errors, including myopia, hyperopia, and astigmatism, are a leading cause of visual impairment among children worldwide. In Saudi Arabia, the prevalence of these conditions among school-age children and adolescents remains poorly understood, with significant variations reported across studies. This systematic review and meta-analysis aimed to provide a comprehensive estimate of the pooled prevalence of refractive errors in this population and explored factors influencing their distribution.
A systematic search of PubMed, Scopus, Web of Science, and ScienceDirect was conducted in accordance with PRISMA 2020 guidelines. Observational studies reporting the prevalence of refractive errors among Saudi school-aged children and adolescents were included. Data extraction and quality assessment were conducted using the Newcastle-Ottawa Scale. Pooled prevalence estimates with 95% confidence intervals (CIs) were calculated using a random-effects model, and heterogeneity was assessed with the I² statistic.
Nine studies including over 15,000 participants were analyzed. The pooled prevalence of myopia was 6.7% (95% CI: 3.0% to 14.2%), hyperopia was 3.6% (95% CI: 1.3% to 9.8%), and astigmatism was 7.7% (95% CI: 2.5% to 20.9%). Subgroup analysis revealed regional disparities, with the highest myopia prevalence reported in Taif (33.3%) and Bisha (22.5%), and the lowest in Medina (1.6%). Studies conducted after 2018 showed a significantly higher pooled myopia prevalence (16.4%, 95% CI: 8% to 30.5%) compared to those published before 2018 (3.3%, 95% CI: 1.4% to 7.5%) (p < 0.001). While studies using cycloplegic refraction reported a slightly higher myopia prevalence (7.2%, 95% CI: 4.7% to 11%) than those using non-cycloplegic methods (6.7%, 95% CI: 2.4% to 17.5%), the difference was not statistically significant (p = 0.9). No significant difference was observed between studies with smaller or larger sample sizes, although high heterogeneity persisted across all subgroups.
Refractive errors, particularly astigmatism, represent a significant and growing public health issue among Saudi school-aged children and adolescents. The findings underscore the urgent need for standardized diagnostic protocols, including the use of cycloplegic refraction, and the implementation of school-based vision screening programs.
屈光不正,包括近视、远视和散光,是全球儿童视力损害的主要原因。在沙特阿拉伯,学龄儿童和青少年中这些情况的患病率仍知之甚少,不同研究报告的患病率差异很大。本系统评价和荟萃分析旨在全面估计该人群屈光不正的合并患病率,并探讨影响其分布的因素。
按照PRISMA 2020指南对PubMed、Scopus、Web of Science和ScienceDirect进行系统检索。纳入报告沙特学龄儿童和青少年屈光不正患病率的观察性研究。使用纽卡斯尔-渥太华量表进行数据提取和质量评估。使用随机效应模型计算合并患病率估计值及其95%置信区间(CI),并使用I²统计量评估异质性。
分析了9项研究,包括超过15000名参与者。近视的合并患病率为6.7%(95%CI:3.0%至14.2%),远视为3.6%(95%CI:1.3%至9.8%),散光为7.7%(95%CI:2.5%至20.9%)。亚组分析显示存在地区差异,塔伊夫(33.3%)和比沙(22.5%)的近视患病率最高,麦地那(1.6%)最低。2018年后进行的研究显示,合并近视患病率(16.4%,95%CI:8%至30.5%)显著高于2018年前发表的研究(3.3%,95%CI:1.4%至7.5%)(p<0.001)。虽然使用睫状肌麻痹验光的研究报告的近视患病率(7.2%,95%CI:4.7%至11%)略高于使用非睫状肌麻痹方法的研究(6.7%,95%CI:2.4%至17.5%),但差异无统计学意义(p=0.9)。样本量较小或较大的研究之间未观察到显著差异,尽管所有亚组均存在高度异质性。
屈光不正,尤其是散光,是沙特学龄儿童和青少年中一个重大且日益严重的公共卫生问题。研究结果强调迫切需要标准化的诊断方案,包括使用睫状肌麻痹验光,并实施基于学校的视力筛查项目。