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成人斯蒂尔病罕见表现合并急性重症肝炎且药物治疗无效:一例报告

Rare Presentation of Adult-Onset Still's Disease Complicated by Acute Severe Hepatitis Refractory to Medical Treatment: A Case Report.

作者信息

Ali Majed, Karam Karam, Dib Emanuel-Youssef, Fiani Elias

机构信息

Department of Internal Medicine University of Balamand Beirut Lebanon.

Department of Gastroenterology University of Balamand Beirut Lebanon.

出版信息

Clin Case Rep. 2025 Jul 8;13(7):e70629. doi: 10.1002/ccr3.70629. eCollection 2025 Jul.

Abstract

Managing adult-onset Still's disease complicated by severe hepatitis requires vigilant monitoring and adaptable therapeutic strategies. Standard treatments such as tocilizumab and rituximab can cause adverse reactions or lose efficacy. The interplay of systemic inflammation and liver involvement highlights the need for ongoing research to find effective, safe treatment alternatives.

摘要

治疗成人斯蒂尔病合并严重肝炎需要密切监测并采取灵活的治疗策略。托珠单抗和利妥昔单抗等标准治疗可能会引起不良反应或失效。全身炎症与肝脏受累之间的相互作用凸显了持续开展研究以寻找有效、安全的替代治疗方法的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcc3/12238314/48b0167d4b9f/CCR3-13-e70629-g001.jpg

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