Ali Majed, Karam Karam, Dib Emanuel-Youssef, Fiani Elias
Department of Internal Medicine University of Balamand Beirut Lebanon.
Department of Gastroenterology University of Balamand Beirut Lebanon.
Clin Case Rep. 2025 Jul 8;13(7):e70629. doi: 10.1002/ccr3.70629. eCollection 2025 Jul.
Managing adult-onset Still's disease complicated by severe hepatitis requires vigilant monitoring and adaptable therapeutic strategies. Standard treatments such as tocilizumab and rituximab can cause adverse reactions or lose efficacy. The interplay of systemic inflammation and liver involvement highlights the need for ongoing research to find effective, safe treatment alternatives.
治疗成人斯蒂尔病合并严重肝炎需要密切监测并采取灵活的治疗策略。托珠单抗和利妥昔单抗等标准治疗可能会引起不良反应或失效。全身炎症与肝脏受累之间的相互作用凸显了持续开展研究以寻找有效、安全的替代治疗方法的必要性。