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镰刀菌性眼内炎的罕见病例：早期诊断和治疗的重要性。

An Unusual Case of Fusarium Endophthalmitis: The Importance of Early Diagnosis and Treatment.

作者信息

Rajendran Jeevakanthi, Chai Jia Wei, Ng Pey Yih, Chang Chee Yik

机构信息

Medicine, Hospital Sultanah Nora Ismail, Batu Pahat, MYS.

Ophthalmology, Hospital Sultanah Nora Ismail, Batu Pahat, MYS.

出版信息

Cureus. 2025 Jun 9;17(6):e85642. doi: 10.7759/cureus.85642. eCollection 2025 Jun.

DOI:10.7759/cureus.85642
PMID:40636600
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12240596/
Abstract

Fusarium endophthalmitis is a rare but devastating ocular infection, often associated with trauma or systemic immunosuppression. It is caused by Fusarium species, a group of filamentous fungi that are widely found in soil and plant material. The infection is characterized by rapid progression and poor visual prognosis if not promptly treated. We present an interesting case of Fusarium endophthalmitis in an immunocompetent elderly male with no prior ocular illness. Early diagnosis and prompt administration of antifungal therapy, including intravitreal amphotericin B and systemic voriconazole, along with surgical intervention, contributed to a favorable clinical outcome.

摘要

镰刀菌性眼内炎是一种罕见但极具破坏性的眼部感染，常与外伤或全身免疫抑制有关。它由镰刀菌属引起，这是一组广泛存在于土壤和植物材料中的丝状真菌。如果不及时治疗，该感染的特点是进展迅速且视力预后不佳。我们报告了一例有趣的镰刀菌性眼内炎病例，患者为一名免疫功能正常的老年男性，既往无眼部疾病。早期诊断并及时给予抗真菌治疗，包括玻璃体内注射两性霉素B和全身应用伏立康唑，同时进行手术干预，促成了良好的临床结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/157b/12240596/29f3a532f7c6/cureus-0017-00000085642-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/157b/12240596/175cebedc5d4/cureus-0017-00000085642-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/157b/12240596/29f3a532f7c6/cureus-0017-00000085642-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/157b/12240596/175cebedc5d4/cureus-0017-00000085642-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/157b/12240596/29f3a532f7c6/cureus-0017-00000085642-i02.jpg

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本文引用的文献

1
Invasive fusariosis.侵袭性镰刀菌病。
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Bilateral Endogenous Endophthalmitis Secondary to Streptococcus pneumoniae: An Uncommon but Devastating Complication.肺炎链球菌所致双侧内源性眼内炎：一种罕见但极具破坏性的并发症
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