Husni Mariwan, Zayed Aldana M, AlSheeroqi Abdulla, Almusalam Maryam, Aldoseri Yousif B, Al-Rayyes Yusuf, Elmahdy Mohamed, Hossam Alya
Psychiatry, Northern Ontario School of Medicine (NOSM) University, Thunder Bay, CAN.
Pharmacy, Knowledge University, Erbil, IRQ.
Cureus. 2025 Jun 9;17(6):e85649. doi: 10.7759/cureus.85649. eCollection 2025 Jun.
Background Migraine is a common neurological disorder with significant socioeconomic and personal impact. Recent research suggests a potential association between migraine and impulsivity, particularly in females. Objective This study aims to investigate the prevalence of impulsivity and its correlation with migraine-related disability in females with migraine. Methods This is a case-control study involving female patients aged 18-60 with migraine, recruited from neurology and psychiatry outpatient clinics. Standardized assessments, including Migraine Disability Assessment (MIDAS), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder 7-item (GAD-7), Barratt Impulsiveness Scale Version 11 (BIS-11), and McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD), were used to evaluate migraine disability, depression, anxiety, and impulsivity. Data analysis was performed using SPSS version 25 (IBM Corp., Armonk, NY, USA). Results There were a total of 149 participants (n=149) in the study, comprising 68 (n=68, 46%) migraine sufferers and 81 (n=81, 54.4%) controls. Migraine patients had significantly higher impulsivity (BIS-11: 34.67 ± 11.95 vs. 26.81 ± 2.99, p < 0.001) and a higher prevalence of borderline personality traits (MSI-BPD: 2.76 ± 2.65 vs. 1.23 ± 0.93, p < 0.01). Depression and anxiety were also significantly more common in the migraine group. Conclusion These findings suggest a strong association between migraine, impulsivity, and mood disorders, emphasizing the need for integrated psychological and neurological management in migraine patients.
偏头痛是一种常见的神经系统疾病，对社会经济和个人都有重大影响。最近的研究表明偏头痛与冲动性之间可能存在关联，尤其是在女性中。目的：本研究旨在调查偏头痛女性患者中冲动性的患病率及其与偏头痛相关残疾的相关性。方法：这是一项病例对照研究，纳入了年龄在18至60岁之间的偏头痛女性患者，这些患者来自神经内科和精神科门诊。使用标准化评估，包括偏头痛残疾评估量表（MIDAS）、患者健康问卷-9（PHQ-9）、广泛性焦虑障碍7项量表（GAD-7）、巴雷特冲动性量表第11版（BIS-11）和边缘型人格障碍麦克林筛查工具（MSI-BPD），来评估偏头痛残疾、抑郁、焦虑和冲动性。使用SPSS 25版软件（美国纽约州阿蒙克市IBM公司）进行数据分析。结果：本研究共有149名参与者（n = 149），其中68名（n = 68，46%）为偏头痛患者，81名（n = 81，54.4%）为对照组。偏头痛患者的冲动性显著更高（BIS-11：34.67 ± 11.95 vs. 26.81 ± 2.99，p < 0.001），边缘型人格特质的患病率也更高（MSI-BPD：2.76 ± 2.65 vs. 1.23 ± 0.93，p < 0.01）。抑郁和焦虑在偏头痛组中也明显更常见。结论：这些发现表明偏头痛、冲动性和情绪障碍之间存在密切关联，强调了对偏头痛患者进行综合心理和神经管理的必要性。
