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使用舒巴坦-阿维巴坦联合治疗耐碳青霉烯类鲍曼不动杆菌(CRAB)菌血症的新方法:病例报告。

A new approach to treat carbapenem resistant (CRAB) bacteremia using sulbactam-avibactam combination: A case report.

作者信息

Alzaidi Sameer, Alharthi Manahil, Alshammamri Hams, Almalki Yasir, Almalki Osama, Alqahtani Shahad, Alosaimi Mohammed, Althumali Nouran

机构信息

Department of Infectious Diseases, King Abdul-Aziz Specialist Hospital, Taif Health Cluster, Taif, Saudi Arabia.

出版信息

IDCases. 2025 Jun 20;41:e02296. doi: 10.1016/j.idcr.2025.e02296. eCollection 2025.

Abstract

Carbapenem resistant (CRAB) infections are serious disease that can be fatal. Only a few therapeutic options are available, with conflicting data for their meaningful clinical outcomes. Here, we report a case of 83-year-old female CRAB bacteremia that was successfully treated with ceftazidime-avibactam and ampicillin-sulbactam combination after failing guidelines directed therapy.

摘要

耐碳青霉烯类(CRAB)感染是一种严重的疾病,可能会致命。目前只有少数治疗选择,且关于其有意义的临床结局的数据相互矛盾。在此,我们报告一例83岁女性CRAB菌血症病例,该患者在指南指导的治疗失败后,采用头孢他啶-阿维巴坦和氨苄西林-舒巴坦联合治疗成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7c9a/12240080/457d1eb1f2da/gr1.jpg

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