Bonifácio Dandara Baia, Macedo Fraiz Gabriela, Lacerda Udielle Vermelho, Cardoso Rodrigo Rezende, Pelissari Kravchychyn Ana Claudia, Corich Viviana, Giacomini Alessio, Ribeiro de Barros Frederico Augusto, Bressan Josefina
Department of Nutrition and Health, Universidade Federal de Viçosa, Viçosa36570-900, Brazil.
Department of Nutrition, Food Science and Physiology, Centre for Nutrition Research, University of Navarra, Pamplona, Spain.
Br J Nutr. 2025 Jul 10:1-9. doi: 10.1017/S0007114525103838.
Kombucha is a fermented beverage rich in bioactive compounds. This beverage has demonstrated high antioxidant capacity and experimental animal studies. In this sense, this study aimed to evaluate the effect of daily consumption of green tea kombucha on oxidative stress and endothelial health in individuals with excess body weight. This is a randomized controlled clinical trial, lasting 10 weeks, during which the control group followed a healthy -500 kcal/d energy-restricted diet. In contrast, the kombucha group, in addition to the energy-restricted diet, consumed 200 ml of kombucha green tea daily. This study included men and women aged 18-45 years without chronic diseases. At the beginning and end of the study, fasting blood was collected, and colorimetric assays and immunoassay protocols evaluated markers of oxidative stress and endothelial health. Compared to the control group, kombucha consumption significantly reduced hydrogen peroxide (HO) levels ( = 0·007). Initial and final values were as follows: Control group (16·5 15·09 µmol/ml; 29) and Kombucha group (18·14 14·67 µmol/ml; 30). The other markers that were evaluated did not change after the kombucha consumption. In conclusion, daily consumption of 200 ml of green tea kombucha for 10 weeks reduces one pro-oxidant marker, without altering other markers of oxidative stress and endothelial health in individuals with excess body weight. Reducing a pro-oxidant marker suggests that kombucha is an antioxidant beverage with promising implications for human health. However, further studies are needed to elucidate other possible beneficial effects on health.
康普茶是一种富含生物活性化合物的发酵饮料。这种饮料在实验动物研究中已显示出高抗氧化能力。从这个意义上说，本研究旨在评估每日饮用绿茶康普茶对体重超标个体氧化应激和内皮健康的影响。这是一项随机对照临床试验，为期10周，在此期间，对照组遵循健康的每日减少500千卡能量的限制饮食。相比之下，康普茶组除了限制能量饮食外，每天还饮用200毫升绿茶康普茶。本研究纳入了18 - 45岁无慢性病的男性和女性。在研究开始和结束时，采集空腹血样，采用比色法和免疫测定法评估氧化应激和内皮健康标志物。与对照组相比，饮用康普茶显著降低了过氧化氢（HO）水平（P = 0·007）。初始值和终值如下：对照组（16·5 ± 15·09微摩尔/毫升；n = 29）和康普茶组（18·14 ± 14·67微摩尔/毫升；n = 30）。评估的其他标志物在饮用康普茶后没有变化。总之，体重超标个体连续10周每天饮用200毫升绿茶康普茶可降低一种促氧化标志物水平，而不改变氧化应激和内皮健康的其他标志物。降低一种促氧化标志物表明康普茶是一种对人类健康有潜在益处的抗氧化饮料。然而，需要进一步研究以阐明其对健康的其他可能有益作用。
