Janardhanachar Rashni Belandor, Gowda Veena Bhaskar S, Purushotham Sapna, Durgad Aishwarya S
Department of Biochemistry, Sri Madhusudan Sai Institute of Medical Sciences and Research (SMSIMSR), Sathya Sai Grama, Muddenahalli, Chikkaballapura, Karnataka, India.
Department of General Surgery, Sri Madhusudan Sai Institute of Medical Sciences and Research (SMSIMSR), Sathya Sai Grama, Muddenahalli, Chikkaballapura, Karnataka, India.
Lung India. 2025 Jul 1;42(4):371-375. doi: 10.4103/lungindia.lungindia_515_24. Epub 2025 Jun 27.
Pancreaticopleural fistula (PPF) is a rare (<1%) complication of acute and/or chronic pancreatitis which causes recurrent massive pleural effusions. Patient presents with respiratory symptoms rather than abdominal symptoms, which makes the diagnosis challenging and delayed. Amylase-rich pleural effusions have been reported in pancreatic diseases, oesophageal rupture, and malignant pleural effusions. Pancreatitis-related effusion including PPF should be kept in mind when a patient with chronic alcohol consumption presents with an effusion and PF amylase may aid with diagnosis. We present a case series of four young males with a history of recurrent massive pleural effusions and their varied clinical presentations, diagnostic work-up, approach and management in a rural tertiary care hospital in south India, thus contributing to literature as well emphasizing the importance of such easily available biomarkers in day-to-day practice.
胰胸膜瘘（PPF）是急性和/或慢性胰腺炎的一种罕见（<1%）并发症，可导致反复大量胸腔积液。患者表现为呼吸道症状而非腹部症状，这使得诊断具有挑战性且会延迟。在胰腺疾病、食管破裂和恶性胸腔积液中均有富含淀粉酶的胸腔积液的报道。当慢性饮酒患者出现胸腔积液时，应考虑胰腺炎相关的积液，包括PPF，且胸腔积液淀粉酶可能有助于诊断。我们报告了一组病例，其中4名年轻男性有反复大量胸腔积液病史，以及他们在印度南部一家农村三级护理医院的不同临床表现、诊断检查、方法和管理，从而为文献做出贡献，并强调了这种易于获得的生物标志物在日常实践中的重要性。
