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成年大鼠外周神经中成熟颈上神经节移植体的活力

Viability of mature superior cervical ganglia transplants in peripheral nerve of adult rat.

作者信息

Hoovler D W, Tang Y, Bernstein J J

出版信息

Brain Res. 1985 Nov 25;348(1):168-74. doi: 10.1016/0006-8993(85)90374-9.

DOI:10.1016/0006-8993(85)90374-9
PMID:4063822
Abstract

Allografts of mature rat superior cervical ganglia (SCG) survived for up to 120 days following transplantation to regenerating and degenerating peripheral nerves of adult rats. Transplants contained the constituents of normal superior cervical ganglia and there was evidence of outgrowth of catecholamine containing fibers from the transplants. However, fibers did not attain the length necessary to enter peripheral muscles and no muscle response could be elicited by electrical stimulation of the implanted nerve where the transplanted mature SCG was the only source of nerve fibers.

摘要

将成熟大鼠颈上神经节(SCG)移植到成年大鼠再生和退变的周围神经后,同种异体移植存活长达120天。移植体包含正常颈上神经节的成分,并且有证据表明移植体中有含儿茶酚胺的纤维长出。然而,纤维并未达到进入周围肌肉所需的长度,并且在植入神经仅以移植的成熟SCG作为神经纤维唯一来源的情况下,电刺激无法引发肌肉反应。

相似文献

1
Viability of mature superior cervical ganglia transplants in peripheral nerve of adult rat.成年大鼠外周神经中成熟颈上神经节移植体的活力
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[Transplantation of the superior cervical ganglion into the brain--a new experimental therapy of Parkinson disease].
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