Pinheiro Hannah Cavalcante Guedes, Silva Mariana Balbino da, Azevedo Girlene Souza de, Santino Thayla Amorim, Campelo Maria Carolina Sarmento, Tavares Jousilene de Sales, Gama Gabriela Lopes, Melo Adriana
Professor Joaquim Amorim Neto Research Institute - Campina Grande (PB), Brazil.
Universidade Estadual da Paraíba - Campina Grande (PB), Brazil.
Rev Assoc Med Bras (1992). 2025 Jul 7;71(6):e20241670. doi: 10.1590/1806-9282.20241670. eCollection 2025.
Children diagnosed with congenital Zika syndrome often experience stomatognathic disorders that may compromise caloric intake via oral feeding.
The aim of this study was to assess the effects of gastrostomy on the growth and nutritional parameters of children with congenital Zika syndrome.
This prospective cohort study included children with congenital Zika syndrome who underwent gastrostomy and were followed up by the Center of Support for Children with Microcephaly in the state of Paraiba, in northeast Brazil. The study was conducted between April 2019 and May 2023. Children were assessed for growth and nutritional parameters using anthropometric measurements (weight, length, and body mass index) and body composition (body fat) around 1 year before gastrostomy (T0), up to 3 months before gastrostomy (T1), and around 1 year after gastrostomy (T2).
A total of 18 children with a mean age of 47.2±18.7 months at the time of gastrostomy were assessed. Significant improvements were observed in weight-for-age (T1=-3.0±1.3 and T2=-2±1.9; p<0.05) after gastrostomy. However, 11.1 and 38.9% of the children remained below or very below the expected weight-for-age, respectively.
Although gastrostomy may increase the anthropometric measures of children with congenital Zika syndrome, this increase may not be enough to achieve adequate weight.
被诊断患有先天性寨卡综合征的儿童常出现口颌系统疾病，这可能会通过经口喂养影响热量摄入。
本研究旨在评估胃造口术对先天性寨卡综合征儿童生长和营养参数的影响。
这项前瞻性队列研究纳入了接受胃造口术的先天性寨卡综合征儿童，并由巴西东北部帕拉伊巴州小头症儿童支持中心进行随访。研究于2019年4月至2023年5月期间进行。在胃造口术前约1年（T0）、胃造口术前3个月（T1）以及胃造口术后约1年（T2），使用人体测量指标（体重、身长和体重指数）和身体成分（体脂）对儿童的生长和营养参数进行评估。
共评估了18名在胃造口术时平均年龄为47.2±18.7个月的儿童。胃造口术后，年龄别体重有显著改善（T1=-3.0±1.3，T2=-2±1.9；p<0.05）。然而，分别有11.1%和38.9%的儿童体重仍低于或远低于预期的年龄别体重。
尽管胃造口术可能会增加先天性寨卡综合征儿童的人体测量指标，但这种增加可能不足以达到足够的体重。
