神经影像学对2019冠状病毒病大流行心理社会影响的见解：一项系统综述
Neuroimaging insights into the psychosocial impact of the COVID-19 pandemic: a systematic review.
作者信息
Guo Yiling, Pan Nanfang, Zou Yuhan, Long Yajing, Zhang Xun, Li Qingyuan, Suo Xueling, Singh Manpreet K, Wang Song, Gong Qiyong
机构信息
Department of Radiology, Huaxi MR Research Center (HMRRC), Institute of Radiology, Functional and Molecular Imaging Key Laboratory of Sichuan Province, West China Hospital of Sichuan University, Chengdu, Sichuan, China.
Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, Sichuan, China.
出版信息
Transl Psychiatry. 2025 Jul 10;15(1):236. doi: 10.1038/s41398-025-03423-2.
The COVID-19 pandemic has posed an unprecedented threat to global health. However, neural substrates underlying mental health vulnerabilities brought by the pandemic remain elusive. We conducted a systematic review relating structural and functional brain abnormalities to mental health issues associated with COVID-19 at brain regional and network levels. A literature search on neuroimaging studies of mental health problems derived by COVID-19 was conducted in the PubMed, Web of Science and MEDLINE databases. We identified 46 studies across various imaging techniques and found that COVID-19-related mental health problems were principally associated with brain structural and functional alterations in the prefrontal cortex, insula, cingulate, hippocampus, and amygdala, as well as the affective cortical network. This review may facilitate the targeted development of therapies tailored to the pandemic context and provide insights for proactive prevention against future collective stressors and traumas.
新冠疫情对全球健康构成了前所未有的威胁。然而，疫情带来的心理健康脆弱性背后的神经基础仍然难以捉摸。我们在脑区和网络层面进行了一项系统综述，将大脑结构和功能异常与新冠疫情相关的心理健康问题联系起来。我们在PubMed、科学网和MEDLINE数据库中对新冠疫情引发的心理健康问题的神经影像学研究进行了文献检索。我们在各种成像技术中确定了46项研究，发现与新冠疫情相关的心理健康问题主要与前额叶皮质、脑岛、扣带回、海马体和杏仁核以及情感皮质网络的大脑结构和功能改变有关。本综述可能有助于针对性地开发适合疫情背景的疗法，并为积极预防未来的集体压力源和创伤提供见解。
Zotero 插件