Kamianowski Aleksander, Kamianowski Cezary, Szpica Gabriela, Jakubas Angelika, Wasilewska Anna, Kamianowska Monika
Department of Neonatology and Neonatal Intensive Care, Medical University of Bialystok, M. C. Sklodowskiej 24a Street, 15-276, Białystok, Poland.
Department of Pediatrics and Nephrology, Medical University of Bialystok, Białystok, Poland.
Sci Rep. 2025 Jul 10;15(1):24849. doi: 10.1038/s41598-025-09500-2.
Reducing neonatal mortality is a crucial part of health-care programs. We wanted to analyze the in-hospital mortality in the tertiary referral Department of Neonatology and Neonatal Intensive Care of the Medical University of Bialystok. The study was conducted on data of all neonates admitted to the Department between 2015 and 2023 (N = 19 171). During the study period the in-hospital mortality rate was 5.16 per 1000 live births and it was the highest in 2021 (8.15 per 1000 live births, p < 0.05). The leading underlying cause of death was extreme prematurity. 43.75% of the extremely preterm or extremely low birth weight neonates had a congenital/hospital acquired infection and 54.69% were not administered a full course of recommended antenatal corticosteroids. The in-hospital mortality rate in the Department was significantly higher than in Poland and other European countries due to the characteristics of the tertiary care Department and was generated mainly by deaths of premature neonates. It was the highest during the period of strict epidemiological restrictions related to the COVD-19 pandemic. Without detailed analyses of neonatal deaths in individual health care facilities and implementation of procedures to improve quality of care, it will not be possible to reduce the number of neonatal deaths.
降低新生儿死亡率是医疗保健项目的关键部分。我们想要分析比亚韦斯托克医科大学三级转诊新生儿科和新生儿重症监护室的院内死亡率。该研究基于2015年至2023年期间该科室收治的所有新生儿数据（N = 19171）。研究期间，院内死亡率为每1000例活产5.16例，2021年最高（每1000例活产8.15例，p < 0.05）。主要潜在死因是极度早产。43.75%的极早产儿或极低出生体重儿患有先天性/医院获得性感染，54.69%未接受推荐的全程产前糖皮质激素治疗。由于三级护理科室的特点，该科室的院内死亡率显著高于波兰和其他欧洲国家，主要由早产儿死亡导致。在与COVID-19大流行相关的严格流行病学限制期间死亡率最高。如果不详细分析各个医疗保健机构的新生儿死亡情况并实施提高护理质量的程序，就不可能减少新生儿死亡数量。
