Charles Malisaba Posite, Woldemichael Mihret Adane, Alpha Muhindo Kavuyiro, Hailu Elias Amare, Halake Samrawit Seyoum, Escalante Elizabeth Vargas, Ndiwelubula Eluzai, Jonas Kambale Makatsi, Sebastiano Nkakyekorera Tindoho, Tumdedo Biruk Abera, Wabinga Henry
Department of Pathology, Kampala International University, Ishaka, Uganda.
Department of Ear, Nose and Throat, Kampala International University, Ishaka, Uganda.
J Med Case Rep. 2025 Jul 10;19(1):334. doi: 10.1186/s13256-025-05242-x.
Adenoid cystic carcinoma is a salivary gland cancer that grows slowly and has an unfavorable prognosis. The occurrence of adenoid cystic carcinoma in the parotid gland is extremely uncommon. It presents in three histopathological patterns: cribriform, tubular, and solid, and it is classified into three grades: grade i, grade ii, and grade III.
We report the case of a 27-year-old female patient from the Ankole tribe, Bantu ethnicity, who had a long-existing, painless lump in her submandibular area and later developed worsening weakness in her lower limbs and back pain. Despite being present for 8 years, the mass was initially attributed to conventional health issues. Diagnostic tests revealed a metastatic adenoid cystic carcinoma of the parotid gland with significant involvement of the spine, which resulted in paraplegia.
This case underscores the insidious nature of adenoid cystic carcinoma, stressing the necessity of early detection and the risks of delayed diagnosis influenced by cultural beliefs and restricted healthcare access. It also highlights the significance of following various steps in the diagnostic process.
腺样囊性癌是一种生长缓慢且预后不良的唾液腺癌。腮腺发生腺样囊性癌极为罕见。它有三种组织病理学模式：筛状、管状和实性，并且分为三个级别：I级、II级和III级。
我们报告一例来自班图族安科莱部落的27岁女性患者，她下颌下区域有一个长期存在的无痛肿块，后来出现下肢无力加重和背痛。尽管该肿块已存在8年，但最初被归因于常见的健康问题。诊断检查显示为腮腺转移性腺样囊性癌，脊柱有明显受累，导致截瘫。
该病例强调了腺样囊性癌的隐匿性，强调了早期检测的必要性以及受文化信仰和医疗服务受限影响而延迟诊断的风险。它还突出了在诊断过程中遵循各个步骤的重要性。
