Delgado-Morales Vilma, Barragán-Maldonado Lizbeth, Salazar-Hernández Mercedes, Talavera-Lopez Alfonso, Ardila Alba N A, Solis-Marcial Oscar Joaquín, Hernández Jose A
Del Instituto Politécnico Nacional, UPIIG, Guanajuato, Mexico.
Departamento de Ingeniería en Minas, Metalurgia y Geología, División de Ingenierías, Universidad de Guanajuato, Guanajuato, Mexico.
Int J Biomater. 2025 Jul 2;2025:9636002. doi: 10.1155/ijbm/9636002. eCollection 2025.
The advancement of science and technology has helped humans solve different problems related to their health. Among these applications are biomaterials, which are materials synthesized by humans for medical or biological use, representing a market and innovation with potential. The best known biomaterials are calcium phosphate cements (CPCs) that are used as bone substitutes, which show a similarity to bone minerals such as apatites such as dicalcium phosphate dihydrate, and it was synthesized and tested in previously prepared simulated intestinal and body fluids to analyze its stability under specific physiological conditions. Purity was determined by the ash method, giving an average of 73% and 85% in the different tests carried out. The characterization study was involved using ATR-FTIR, XRD, SEM, and EDS where changes were observed in the crystalline structure, in the bonds of the functional groups present on the surface and the morphology of Brushite causing the interaction with the different simulated fluids transformation into monetite, amorphous dicalcium phosphate, and hydroxyapatite.
科学技术的进步帮助人类解决了与健康相关的各种问题。这些应用中包括生物材料，生物材料是人类合成的用于医学或生物学用途的材料，代表着一个具有潜力的市场和创新领域。最著名的生物材料是用作骨替代物的磷酸钙骨水泥（CPCs），它与诸如二水磷酸二钙等磷灰石类骨矿物质相似，并且已在先前制备的模拟肠液和体液中进行合成和测试，以分析其在特定生理条件下的稳定性。通过灰化法测定纯度，在进行的不同测试中平均纯度分别为73%和85%。表征研究使用了衰减全反射傅里叶变换红外光谱（ATR-FTIR）、X射线衍射（XRD）、扫描电子显微镜（SEM）和能谱仪（EDS），观察到在晶体结构、表面存在的官能团的键以及透钙磷石的形态方面发生了变化，导致其与不同模拟液相互作用转化为磷酸一钙、无定形磷酸二钙和羟基磷灰石。
