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生殖器女性化手术的手术并发症及危险因素分析:一项对407名跨性别女性的回顾性队列研究。

Analysis of surgical complications and risk factors in genital feminization surgery: a retrospective cohort study of 407 transgender women.

作者信息

Ferchichi Fériel, Morel-Journel Nicolas, Carnicelli Damien, Freton Lucas, Jurek Lucie, Ruffion Alain, Madec François-Xavier, Neuville Paul

机构信息

Urology Department, Hospital Lyon Sud, Hospices civils de Lyon, Lyon 69310, France.

Claude Bernard University Lyon 1, Villeurbanne  69000, France.

出版信息

Sex Med. 2025 Jul 10;13(3):qfaf045. doi: 10.1093/sexmed/qfaf045. eCollection 2025 Jun.

Abstract

BACKGROUND

Penile inversion vulvo-vaginoplasty with addition of a scrotal skin graft is a widely used technique in genital feminizing surgery for trans women.

AIM

To identify the types and frequencies of complications following genital feminizing surgery and assess associated risk factors.

METHODS

A retrospective review was conducted on all trans women who underwent primary genital feminizing surgery at Lyon Sud University Hospital between 2008 and 2022. Inclusion criteria were age over 18 and a minimum follow-up of 1 year. Data were collected from electronic medical records and included demographic and clinical characteristics, surgical details, intraoperative events, postoperative complications, and revision procedures.

OUTCOMES

The study focused on the incidence of intraoperative, early, and late postoperative complications, as well as the frequency and types of surgical revisions.

RESULTS

Among 407 patients (mean (SD) age of 38.6 (12.7) years, mean (SD) BMI of 24.7), intra-operative rectal injury occurred in 5 patients (1.2%). Early graft failure requiring revision was seen in 1%, and 23.1% underwent secondary revisions. Late complications included recto-neovaginal fistula (0.5%) and vaginal stenosis requiring revision (3.4%). Labiaplasty was the most frequent revision procedure ( = 68). Younger age was associated with increased early revisions, while BMI and smoking were not.

CLINICAL IMPLICATIONS

Clear, individualized preoperative counseling is essential to prepare patients for the potential need for revision surgery.

STRENGTHS & LIMITATIONS: This study benefits from a large sample size and long follow-up but is limited by its retrospective design and reliance on electronic records.

CONCLUSION

Penile inversion vulvo-vaginoplasty with scrotal skin graft is a generally safe procedure; detailed knowledge of complications supports better patient counseling and informed decision-making.

摘要

背景

阴茎翻转外阴阴道成形术联合阴囊皮肤移植是跨性别女性生殖器女性化手术中广泛使用的技术。

目的

确定生殖器女性化手术后并发症的类型和发生率,并评估相关危险因素。

方法

对2008年至2022年在里昂南大学医院接受初次生殖器女性化手术的所有跨性别女性进行回顾性研究。纳入标准为年龄超过18岁且至少随访1年。数据从电子病历中收集,包括人口统计学和临床特征、手术细节、术中情况、术后并发症及修复手术。

结果

该研究聚焦于术中、术后早期和晚期并发症的发生率,以及手术修复的频率和类型。

结果

在407例患者中(平均(标准差)年龄为38.6(12.7)岁,平均(标准差)体重指数为24.7),5例患者(1.2%)术中发生直肠损伤。1%的患者出现早期移植失败需要修复,23.1%的患者接受了二次修复。晚期并发症包括直肠新阴道瘘(0.5%)和需要修复的阴道狭窄(3.4%)。阴唇成形术是最常见的修复手术(n = 68)。年龄较小与早期修复增加相关,而体重指数和吸烟则无关。

临床意义

清晰、个性化的术前咨询对于让患者为可能需要的修复手术做好准备至关重要。

优点和局限性

本研究样本量大且随访时间长,但受回顾性设计和对电子记录的依赖所限。

结论

阴茎翻转外阴阴道成形术联合阴囊皮肤移植总体上是一种安全的手术;对并发症的详细了解有助于更好地为患者提供咨询和做出明智的决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6dc5/12240733/b90950e0f802/qfaf045f1.jpg

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