López-Ferreruela Irene, Gimeno-Miguel Antonio, Laguna-Berna Clara, Malo Sara, Castel-Feced Sara, José Rabanaque María, Aguilar-Palacio Isabel
Torreramona Health Centre, Primary Care, Servicio Aragonés de Salud (SALUD), Zaragoza, Spain.
Grupo de Investigación en Servicios Sanitarios de Aragón (GRISSA), Fundación Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Zaragoza, Spain.
Front Glob Womens Health. 2025 Jun 26;6:1605400. doi: 10.3389/fgwh.2025.1605400. eCollection 2025.
Secondary prevention after an acute myocardial infarction (AMI) has the objective of improving quality of life, minimizing recurrence, and reducing morbidity and mortality. Despite European guidelines highlighting the importance of cardiovascular risk factor (CVRF) management and optimal healthcare utilization, inequalities persist, particularly between genders. This study aims to identify and analyze gender inequalities in healthcare utilization and CVRF monitoring during the first year after AMI using real-world data (RWD).
An analytical study was conducted within the CARhES (CArdiovascular Risk factors for Health Services research) cohort in Aragon, Spain. The study population included 3,464 subjects who survived a first AMI and were followed for one full year after the event. Sociodemographic, anthropometric, clinical data, healthcare utilization, CVRF monitoring and pharmacological prescriptions, were extracted from the Aragon Health Service. Statistical analyses included chi-squared tests, Student's -tests, and logistic regression, with Blinder-Oaxaca decomposition applied to explore possible explanatory factors for gender differences.
Women represented 28.3% of the study population. Compared with men, they were older and had a higher morbidity burden. Primary care utilization was similar between genders; however, women had fewer cardiology visits ( < 0.001) and were less likely to achieve risk factor monitoring goals. Differences were also observed in pharmacological treatment, with women being less likely to receive beta-blockers, lipid modifying agents, and antiplatelet agents ( < 0.001). Several of these inequalities persisted after controlling for age. The Oaxaca decomposition showed that age and morbidity burden were the main contributors to gender disparities. In addition, socioeconomic status and place of residence played a role in health services utilization differences.
Gender inequalities are still present in post-AMI care and CVRF management, with women being more likely to receive less adequate treatment and management. Addressing these inequalities is crucial to ensuring equitable care and improving health outcomes for women.
急性心肌梗死(AMI)后的二级预防旨在提高生活质量、减少复发,并降低发病率和死亡率。尽管欧洲指南强调了心血管危险因素(CVRF)管理和优化医疗保健利用的重要性,但不平等现象依然存在,尤其是在性别之间。本研究旨在利用真实世界数据(RWD)识别和分析AMI后第一年医疗保健利用和CVRF监测中的性别不平等情况。
在西班牙阿拉贡的CARhES(卫生服务研究中的心血管危险因素)队列中进行了一项分析性研究。研究人群包括3464名首次AMI存活且事件发生后随访一整年的受试者。从阿拉贡卫生服务机构提取了社会人口统计学、人体测量学、临床数据、医疗保健利用、CVRF监测和药物处方信息。统计分析包括卡方检验、学生t检验和逻辑回归,并应用布林德-奥萨卡分解来探索性别差异的可能解释因素。
女性占研究人群的28.3%。与男性相比, 她们年龄更大且发病负担更高。两性的初级保健利用率相似;然而,女性看心脏病专科的次数更少(<0.001),且实现危险因素监测目标的可能性更低。在药物治疗方面也观察到差异,女性接受β受体阻滞剂、调脂药和抗血小板药物的可能性更小(<0.001)。在控制年龄后,其中一些不平等现象仍然存在。奥萨卡分解表明,年龄和发病负担是性别差异的主要因素。此外,社会经济地位和居住地点在医疗服务利用差异中也起了作用。
AMI后护理和CVRF管理中仍存在性别不平等,女性更有可能接受不太充分的治疗和管理。解决这些不平等对于确保公平护理和改善女性健康结局至关重要。