Chevalley B, Betello M, Blavakis E, Malclès A, Maillard J
Division of Anaesthesiology, Department of Acute Care Medicine Geneva University Hospitals Geneva Switzerland.
Department of Ophthalmology Geneva University Hospitals Geneva Switzerland.
Anaesth Rep. 2025 Jul 9;13(2):e70020. doi: 10.1002/anr3.70020. eCollection 2025 Jul-Dec.
A 32-year-old woman presented with transient visual loss following the intra-operative administration of a single intravenous dose of tranexamic acid during urgent cholecystectomy. Apart from obesity, the patient had no notable medical history or pre-existing ocular conditions. Immediately after surgery, the patient reported sudden onset blindness. Ophthalmological and radiologic assessments did not reveal any detectable macrovascular or organic ophthalmic lesions. The patient's vision gradually improved spontaneously, with the resolution of the dyschromatopsia on the first postoperative day and complete recovery by the second postoperative day. This case highlights the importance of prompt investigation of acute visual impairment postoperatively and identifying potential causative agents, such as tranexamic acid.
一名32岁女性在急诊胆囊切除术期间静脉注射一剂氨甲环酸后出现短暂性视力丧失。除肥胖外，患者无明显病史或既往眼部疾病。术后患者立即报告突然失明。眼科和放射学评估未发现任何可检测到的大血管或器质性眼科病变。患者视力逐渐自发改善，术后第一天色觉异常消失，术后第二天完全恢复。该病例强调了术后及时调查急性视力损害并识别潜在病因（如氨甲环酸）的重要性。
