Liu Juan, Wang Yanjing, Zhang Haoyang, Liu Tingjiao
Department of Oral Pathology, Shanghai Stomatological Hospital and School of Stomatology, Fudan University Shanghai, China.
Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University Shanghai, China.
Int J Clin Exp Pathol. 2025 Jun 15;18(6):274-284. doi: 10.62347/QBAS2730. eCollection 2025.
Myopericytoma (MPC) is a rare, benign, and cellular mesenchymal neoplasm. Histologically, it is characterized by concentric perivascular proliferation of spindle-shaped tumor cells. While MPCs predominantly occur in the subcutaneous or superficial soft tissues of distal extremities, oral MPCs are exceptionally rare. Herein, we present a case of MPC located in the sublingual region of a 74-year-old male. Additionally, we conducted a systematic review of 29 previously reported cases to delineate the clinicopathological and molecular features of MPC. This comprehensive analysis aims to improve diagnostic accuracy and enhance the cognition of this uncommon tumor entity's clinicopathological characteristics and biological behavior.
肌周细胞瘤（MPC）是一种罕见的、良性的细胞性间叶肿瘤。组织学上，其特征为梭形肿瘤细胞呈同心圆状围绕血管增生。虽然MPC主要发生于远端肢体的皮下或浅表软组织，但口腔MPC极为罕见。在此，我们报告一例位于一名74岁男性舌下区域的MPC病例。此外，我们对29例先前报道的病例进行了系统回顾，以描述MPC的临床病理和分子特征。这一综合分析旨在提高诊断准确性，并增进对这种罕见肿瘤实体的临床病理特征和生物学行为的认识。
