Suppr超能文献

通过转座子诱变结合下一代测序(Tn-seq)鉴定酸生长停滞的遗传决定因素。

Identifying genetic determinants of acid growth arrest by transposon mutagenesis coupled with next-generation sequencing (Tn-seq).

作者信息

Healy Claire, Ioerger Thomas R, Ehrt Sabine, Gouzy Alexandre

机构信息

School of Medicine, Trinity College Dublin, Dublin, Ireland.

Department of Computer Science and Engineering, Texas A&M University, College Station, Texas, USA.

出版信息

Microbiol Resour Announc. 2025 Aug 14;14(8):e0006025. doi: 10.1128/mra.00060-25. Epub 2025 Jul 11.

Abstract

the causative agent of tuberculosis, remains the leading global infectious disease killer. Adaptation of to acidic niches within the host during infection is vital to establish the disease. Here, we present a high-density transposon mutant sequencing library data set identifying genetic determinants of acid growth arrest to serve as a resource.

摘要

结核病的病原体仍然是全球主要的感染性疾病杀手。在感染过程中,结核杆菌适应宿主内的酸性微环境对于引发疾病至关重要。在此,我们提供了一个高密度转座子突变体测序文库数据集,以鉴定酸生长停滞的遗传决定因素,作为一种资源。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1135/12352093/bc16e4d87d10/mra.00060-25.f001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验