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商业航班上发生过敏反应的风险。

Risk of anaphylaxis on commercial flights.

作者信息

Turner Paul J

机构信息

National Heart & Lung Institute, Imperial College London, London, UK.

出版信息

Curr Opin Allergy Clin Immunol. 2025 Oct 1;25(5):336-342. doi: 10.1097/ACI.0000000000001090. Epub 2025 Jul 11.

DOI:10.1097/ACI.0000000000001090
PMID:40643054
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12404620/
Abstract

PURPOSE OF REVIEW

Air travel has now returned to prepandemic levels, with over 10.5 billion passengers in 2024. Many of these passengers have food allergies, and there is a perception that allergic reactions are common during commercial flights.

RECENT FINDINGS

A recent systematic review and meta-analysis reported an incidence of in-flight medical events due to allergic reactions of 0.7 (95% CI 0.4-1.1) events per million passengers. For those with food allergies, the incidence of allergic reactions is around 10-100 times lower than that reported for reactions 'on the ground' - equivalent to one reaction per 3600 food-allergic passengers in any 1-year period. Reassuringly, there is no evidence that this rate had increased over the past 30 years, despite significant increases in both the prevalence of food allergy and passenger numbers.

SUMMARY

Allergic reactions during commercial flights are uncommon; however, this is very likely to be confounded by the many precautions food-allergic passengers and their families take when flying. Nonetheless, the data confirm that flying can be safe for those with food allergies. While air travel continues to present numerous challenges to those with food allergy, this can be mitigated by consistent and helpful airline policies, which address the concerns of food-allergic individuals.

摘要

综述目的

航空旅行现已恢复到疫情前的水平,2024年旅客超过105亿人次。这些旅客中有许多人患有食物过敏,人们认为在商业航班飞行期间过敏反应很常见。

最新发现

最近一项系统评价和荟萃分析报告称,因过敏反应导致的飞行中医疗事件发生率为每百万乘客0.7起(95%置信区间0.4 - 1.1)。对于食物过敏者,过敏反应的发生率比“地面”反应报告的发生率低约10 - 100倍——相当于每3600名食物过敏乘客在任何1年期间发生1次反应。令人欣慰的是,尽管食物过敏患病率和乘客数量都显著增加,但没有证据表明在过去30年里这一发生率有所上升。

总结

商业航班飞行期间的过敏反应并不常见;然而,这很可能被食物过敏乘客及其家人在飞行时采取的许多预防措施所混淆。尽管如此,数据证实飞行对食物过敏者来说是安全的。虽然航空旅行继续给食物过敏者带来诸多挑战,但通过一致且有益的航空公司政策可以缓解这些问题,这些政策能解决食物过敏者的担忧。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/a73600fbc9f7/coaci-25-336-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/6d4b6eff825e/coaci-25-336-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/df6b5e35ee19/coaci-25-336-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/93378a640edd/coaci-25-336-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/a73600fbc9f7/coaci-25-336-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/6d4b6eff825e/coaci-25-336-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/df6b5e35ee19/coaci-25-336-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/93378a640edd/coaci-25-336-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/530c/12404620/a73600fbc9f7/coaci-25-336-g004.jpg

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本文引用的文献

1
Understanding Experiences, Barriers, and Facilitators of Safe Airline Travel: A Global Survey of Food Allergy Patients and Caregivers.了解安全航空旅行的经历、障碍和促进因素:一项针对食物过敏患者及其护理人员的全球调查。
J Allergy Clin Immunol Pract. 2024 Dec;12(12):3372-3382. doi: 10.1016/j.jaip.2024.08.045.
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Flying with nut and other food allergies: unravelling fact from fiction.携带坚果及其他食物过敏乘坐飞机:拨开事实与虚构的迷雾
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Allergic reactions during travel among individuals with IgE-mediated food allergy.
IgE介导的食物过敏个体在旅行期间的过敏反应。
J Allergy Clin Immunol Pract. 2024 Mar;12(3):774-775. doi: 10.1016/j.jaip.2023.10.042. Epub 2023 Nov 3.
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How Common Are Allergic Reactions During Commercial Flights? A Systematic Review and Meta-Analysis.在商业航班中过敏反应的发生率有多高?系统评价和荟萃分析。
J Allergy Clin Immunol Pract. 2023 Nov;11(11):3400-3406.e4. doi: 10.1016/j.jaip.2023.07.025. Epub 2023 Jul 26.
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Who Needs Epinephrine? Anaphylaxis, Autoinjectors, and Parachutes.谁需要肾上腺素?过敏反应、自动注射器和降落伞。
J Allergy Clin Immunol Pract. 2023 Apr;11(4):1036-1046. doi: 10.1016/j.jaip.2023.02.002. Epub 2023 Feb 14.
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Going on vacation increases risk of severe accidental allergic reaction in children and adolescents.度假会增加儿童和青少年发生严重意外过敏反应的风险。
Ann Allergy Asthma Immunol. 2023 Apr;130(4):516-518. doi: 10.1016/j.anai.2022.12.026. Epub 2022 Dec 24.
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The frequency and characteristics of epinephrine use during in-flight allergic events.飞行中过敏事件期间肾上腺素使用的频率及特征。
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The global incidence of in-flight medical emergencies: A systematic review and meta-analysis of approximately 1.5 billion airline passengers.机上医疗紧急情况的全球发病率:对约15亿航空乘客的系统评价和荟萃分析。
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