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[喉咽反流疾病——2025年更新:结合欧洲耳鼻咽喉头颈外科学会指南的修订版]

[Laryngopharyngeal reflux disease-update 2025 : Revision taking into consideration the European CEORL-HNS guideline].

作者信息

Böttcher Arne, Schmitz Lisa, Trache Mihnea C, Stortz Ulrich, Clausen Jacob F, Betz Christian S

机构信息

Klinik und Poliklinik für Hals‑, Nasen- und Ohrenheilkunde, Kopf- und Neurozentrum, Universitätsklinikum Hamburg-Eppendorf, Martinistraße 52, 20251, Hamburg, Deutschland.

Klinik für Innere Medizin I: Gastroenterologie, Schwarzwald-Baar Klinikum, Villingen-Schwenningen, Deutschland.

出版信息

HNO. 2025 Jul 9. doi: 10.1007/s00106-025-01645-w.

Abstract

Laryngopharyngeal reflux disease (LPRD), a common condition with a variety of symptoms, often occurs without heartburn. One of the main causes appears to be the pepsin effect. Systematic recording of symptoms and findings confirms the suspected diagnosis. A patient-individualized multimodal therapy plan can quickly provide relief. Lifestyle modifications and treatment with alginate and proton pump inhibitors are often effective. Carcinophobic patients with foreign body sensation should be informed in detail and, in case of doubt, malignancy should be ruled out. This CME training course provides an overview of the current state of knowledge and refers to the recently published European guideline of the Confederation of European Otorhinolaryngology-Head and Neck Surgery Societies (CEORL-HNS).

摘要

喉咽反流病(LPRD)是一种常见疾病,症状多样,常无烧心症状。其主要病因之一似乎是胃蛋白酶的作用。系统记录症状和检查结果可确诊疑似病例。个体化的多模式治疗方案能迅速缓解症状。生活方式调整以及使用藻酸盐和质子泵抑制剂进行治疗通常有效。对于有异物感且恐癌的患者,应详细告知情况,如有疑问,应排除恶性肿瘤。本继续医学教育培训课程概述了当前的知识状况,并参考了欧洲耳鼻咽喉头颈外科学会联合会(CEORL-HNS)最近发布的欧洲指南。

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