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针对精神分裂症谱系障碍成年人的基于虚拟小组的步行干预:一项试点随机对照试验的心理社会结果

Virtual Group-based Walking Intervention for Adults with Schizophrenia-Spectrum Disorders: Psychosocial Outcome Results from a Pilot Randomized Controlled Trial.

作者信息

Browne Julia, Kunicki Zachary, Jarskog L Fredrik, Sheeran Paschal, Abrantes Ana M, Elliott Tonya, Gonzalez Oscar, Penn David L, Battaglini Claudio

机构信息

Transformative Health Systems Research to Improve Veteran Equity and Independence (THRIVE) Center of Innovation, VA Providence Healthcare System, 830 Chalkstone Avenue, Providence, 02908, RI, USA.

Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.

出版信息

Community Ment Health J. 2025 Jul 11. doi: 10.1007/s10597-025-01488-3.

Abstract

Physical activity improves mental health in individuals with schizophrenia. Yet, limited access, low motivation, and social isolation make participation in face-to-face programs challenging. This 16-week pilot randomized controlled trial examined differences in symptoms and loneliness between adults with schizophrenia that were randomized to a virtual group-based walking program ("Virtual PACE-Life", n = 17) or Fitbit Alone (n = 20). The Positive and Negative Syndrome Scale and UCLA Loneliness scale were administered at baseline, 8 weeks, 16 weeks, and one-month follow-up. Standardized effects (SE) and confidence intervals from mixed effects models were used to evaluate group differences. Results demonstrated small-to-moderate effects (SE: 0.1-0.3) on total, negative, disorganization, excitement, and emotional distress symptoms favoring Virtual PACE-Life; however, negligible effects were observed for positive symptoms or loneliness. Despite the small sample size, these findings may suggest symptom but not loneliness benefits of a virtual group-based physical activity program for people with schizophrenia.

摘要

体育活动可改善精神分裂症患者的心理健康。然而,机会有限、动力不足和社会隔离使得参与面对面项目具有挑战性。这项为期16周的试点随机对照试验,研究了被随机分配到虚拟团体步行项目(“虚拟PACE-生活”,n = 17)或仅使用Fitbit(n = 20)的精神分裂症成年患者在症状和孤独感方面的差异。在基线、第8周、第16周和1个月随访时,使用阳性和阴性症状量表以及加州大学洛杉矶分校孤独感量表进行评估。混合效应模型的标准化效应(SE)和置信区间用于评估组间差异。结果表明,在总症状、阴性症状、紊乱症状、兴奋症状和情绪困扰症状方面,虚拟PACE-生活组有小到中等程度的效应(SE:0.1-0.3);然而,阳性症状或孤独感方面的效应可忽略不计。尽管样本量较小,但这些发现可能表明,基于虚拟团体的体育活动项目对精神分裂症患者有改善症状的作用,但对孤独感没有作用。

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