The impact of multimodal high intensity exercise program comparing online and onsite interventions in breast cancer survivors: a randomized controlled trial.

PURPOSE

Cancer frequently leads to reduced cardiorespiratory fitness (CRF), altered body composition, and increased fatigue, negatively impacting quality of life. This study aimed to evaluate the effects of a multimodal oncological exercise program on CRF, body composition, functional capacity, fatigue, and quality of life in breast cancer survivors.

METHODS

Seventy-four breast cancer survivors (stages IA-IIIB) were randomized to either an intervention group (n = 40), participating in a 16-week, twice-weekly multimodal exercise program (in-person or online), or a control group (n = 34). CRF was the primary outcome. Measurements were taken at baseline and post-intervention.

RESULTS

The intervention group showed significant improvements in CRF (+22.4%), fat mass (-10%), and lean mass (+5.24%). Functional capacity and physical activity levels also increased. No significant differences were found between in-person and online delivery formats, suggesting the effectiveness of remote interventions.

CONCLUSIONS

A 16-week structured, multimodal exercise program significantly improved CRF, body composition, and physical function in breast cancer survivors. Comparable outcomes between in-person and online formats support the feasibility and utility of remote exercise programs in oncology care.