Lope Virginia, Guerrero-Zotano Angel, Ruiz-Moreno Emma, Bermejo Begoña, Antolín Silvia, Montaño Álvaro, Baena-Cañada José Manuel, Ramos Vázquez Manuel, Fernández de Larrea-Baz Nerea, Chacón José Ignacio, García-Sáenz José Angel, Olier Clara, Muñoz Montserrat, Antón Antonio, Sánchez Rovira Pedro, Arcusa Lanza Angels, González Sonia, Oltra Amparo, Brunet Joan, Gavilá Gregori Joaquín, Martínez María Teresa, Calvo Lourdes, Rosell Libertad, Bezares Susana, Pastor-Barriuso Roberto, Pérez-Gómez Beatriz, Martín Miguel, Pollán Marina
Department of Epidemiology of Chronic Diseases, National Center for Epidemiology, Instituto de Salud Carlos III, Avda. Monforte de Lemos 5, 28029 Madrid, Spain.
Consortium for Biomedical Research in Epidemiology & Public Health (CIBERESP), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Cancers (Basel). 2022 Sep 27;14(19):4705. doi: 10.3390/cancers14194705.
Breast cancer (BC) survivors are advised to follow the WCRF/AICR cancer prevention recommendations, given their high risk of developing a second tumour. We aimed to explore compliance with these recommendations in BC survivors and to identify potentially associated clinical and sociodemographic factors. A total of 420 BC survivors, aged 31-80, was recruited from 16 Spanish hospitals. Epidemiological, dietary and physical activity information was collected through questionnaires. A 7-item score to measure compliance with the recommendations was built according to the 2018 WCRF/AICR scoring criteria. Standardized prevalences and standardized prevalence ratios of moderate and high compliance across participant characteristics were estimated using multinomial and binary logistic regression models. The mean score was 3.9 (SD: 1.0) out of 7 points. Recommendations with the worst adherence were those of limiting consumption of red/processed meats (12% of compliance, 95% CI: 8.2-15.0) and high fibre intake (22% of compliance, 95% CI: 17.6-27.0), while the best compliance was observed for the consumption of fruits and vegetables (73% of compliance, 95% CI: 69.2-77.7). Overall, adherence was worse in women with university education and in those with first-degree relatives with BC. This information may be of interest to design and implement personalized preventive measures adapted to the characteristics of these patients.
鉴于乳腺癌（BC）幸存者患第二种肿瘤的风险较高，建议他们遵循世界癌症研究基金会/美国癌症研究协会（WCRF/AICR）的癌症预防建议。我们旨在探讨BC幸存者对这些建议的依从性，并确定潜在相关的临床和社会人口学因素。从16家西班牙医院招募了总共420名年龄在31至80岁之间的BC幸存者。通过问卷调查收集了流行病学、饮食和身体活动信息。根据2018年WCRF/AICR评分标准建立了一个7项评分来衡量对建议的依从性。使用多项和二元逻辑回归模型估计了参与者特征中中度和高度依从性的标准化患病率和标准化患病率比。平均得分为3.9分（标准差：1.0），满分7分。依从性最差的建议是限制红肉/加工肉类的摄入量（依从率为12%，95%置信区间：8.2 - 15.0）和高纤维摄入量（依从率为22%，95%置信区间：17.6 - 27.0），而水果和蔬菜的摄入量依从性最好（依从率为73%，95%置信区间：69.2 - 77.7）。总体而言，受过大学教育的女性以及有BC一级亲属的女性依从性较差。这些信息可能有助于设计和实施适合这些患者特征的个性化预防措施。
