Merrick M V, Merrick J M
Clin Radiol. 1985 Mar;36(2):169-74. doi: 10.1016/s0009-9260(85)80103-3.
Whole-body skeletal scintigraphy was performed in 4700 adult patients from south-east Scotland. In 3831 with proven or suspected malignant disease the prevalence of osteitis deformans in males is 0.006 in those aged 15-54 years, 0.026 in the age group 55-84 years and 0.24 over the age of 84 years. The corresponding figures in females are 0.002, 0.021 and 0.15. Previous estimates of prevalence should be increased by at least 25% to take account of peripheral and monostotic disease, which is more common than hitherto recognised. The increase in prevalence with age may not be linear. Possible associations with environmental and genetic factors which would account for such a distribution are considered. It is suggested that the conventional distinction between 'active' and 'burned out' Paget's disease may be incorrect.
对来自苏格兰东南部的4700名成年患者进行了全身骨骼闪烁扫描。在3831名已证实或疑似患有恶性疾病的患者中，男性15至54岁组畸形性骨炎的患病率为0.006，55至84岁年龄组为0.026，84岁以上为0.24。女性的相应数字分别为0.002、0.021和0.15。先前对患病率的估计应至少提高25%，以考虑到周围性和单骨型疾病，这类疾病比迄今所认识到的更为常见。患病率随年龄的增长可能不是呈线性的。文中考虑了可能与环境和遗传因素有关的情况，这些因素可以解释这种分布。有人提出，传统上对“活动期”和“静止期”佩吉特病的区分可能是不正确的。
