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Interleukin-6 is a highly prognostic biomarker for POEMS syndrome.

作者信息

Cook Joselle, Warsame Rahma, Omar Maryam, Buadi Francis K, Abdallah Nadine, Dingli David, Hayman Suzanne R, Kapoor Prashant, Kourelis Taxiarchis, Binder Moritz, Muchtar Eli, Fonder Amie, Hwa Yi L, Hobbs Miriam A, Lin Yi, Gonsalves Wilson I, Gertz Morie A, Kumar Shaji K, Rajkumar S Vincent, Dispenzieri Angela

机构信息

Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.

出版信息

Leukemia. 2025 Jul 11. doi: 10.1038/s41375-025-02659-7.

DOI:10.1038/s41375-025-02659-7
PMID:40646134
Abstract
摘要

相似文献

1
Interleukin-6 is a highly prognostic biomarker for POEMS syndrome.白细胞介素-6是POEMS综合征的一种高度预后生物标志物。
Leukemia. 2025 Jul 11. doi: 10.1038/s41375-025-02659-7.
2
Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome.POEMS（多发性神经病变、器官肿大、内分泌病、M蛋白和皮肤改变）综合征的治疗。
Cochrane Database Syst Rev. 2012 Jun 13;2012(6):CD006828. doi: 10.1002/14651858.CD006828.pub3.
3
Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome.POEMS（多发性神经病变、器官肿大、内分泌病、M蛋白和皮肤改变）综合征的治疗。
Cochrane Database Syst Rev. 2008 Oct 8(4):CD006828. doi: 10.1002/14651858.CD006828.pub2.
4
Delayed Diagnosis of Poems Syndrome, How AI Tools Can Enhance Diagnostic Accuracy.POEMS综合征的延迟诊断，人工智能工具如何提高诊断准确性。
Eur J Case Rep Intern Med. 2025 Jun 5;12(7):005504. doi: 10.12890/2025_005504. eCollection 2025.
5
Unicentric Castleman disease following POEMS syndrome remission.POEMS综合征缓解后出现的单中心Castleman病。
J Hematop. 2025 Jul 10;18(1):31. doi: 10.1007/s12308-025-00646-6.
6
POEMS syndrome presenting with -like cutaneous lesions: a CARE guidelines-compliant case report.以苔藓样皮肤损害为表现的POEMS综合征：一份符合CARE指南的病例报告。
Front Med (Lausanne). 2025 Jul 8;12:1625877. doi: 10.3389/fmed.2025.1625877. eCollection 2025.
7
A case report of an M protein-negative patient with POEMS syndrome associated with renal involvement.一例伴有肾脏受累的POEMS综合征的M蛋白阴性患者的病例报告。
BMC Nephrol. 2024 Dec 24;25(1):472. doi: 10.1186/s12882-024-03898-z.
8
A case report of Castleman disease variant of POEMS syndrome presenting with prominent polyserositis and renal impairment.1例以显著多浆膜炎和肾功能损害为表现的POEMS综合征Castleman病变异型病例报告
Front Med (Lausanne). 2025 Jun 16;12:1537944. doi: 10.3389/fmed.2025.1537944. eCollection 2025.
9
Successful treatment with carfilzomib and dexamethasone for relapsed/refractory POEMS syndrome: a case report and review of literature.卡非佐米和地塞米松成功治疗复发/难治性POEMS综合征：一例报告及文献复习
Front Oncol. 2025 Jun 6;15:1570981. doi: 10.3389/fonc.2025.1570981. eCollection 2025.
10
[Chinese expert consensus on the diagnosis and treatment of POEMS syndrome (2025)].《POEMS综合征诊断与治疗中国专家共识（2025年版）》
Zhonghua Xue Ye Xue Za Zhi. 2025 May 14;46(5):389-396. doi: 10.3760/cma.j.cn121090-20241219-00578.

本文引用的文献

1
POEMS syndrome: Update on diagnosis, risk-stratification, and management.POEMS综合征：诊断、风险分层及管理的最新进展
Am J Hematol. 2023 Dec;98(12):1934-1950. doi: 10.1002/ajh.27081. Epub 2023 Sep 21.
2
VEGF and IL-6 Correlation in POEMS: a Potential Upcoming Marker of Active Disease and Early Autologous BMT Response.POEMS综合征中血管内皮生长因子与白细胞介素-6的相关性：活动性疾病和早期自体骨髓移植反应的潜在新标志物
Mediterr J Hematol Infect Dis. 2022 Jan 1;14(1):e2022007. doi: 10.4084/MJHID.2022.007. eCollection 2022.
3
Prognostic study for overall survival in patients with newly diagnosed POEMS syndrome.
新诊断 POEMS 综合征患者总生存预后研究。
Leukemia. 2017 Jan;31(1):100-106. doi: 10.1038/leu.2016.168. Epub 2016 Jun 13.
4
Long-term outcome of patients with POEMS syndrome: An update of the Mayo Clinic experience.POEMS 综合征患者的长期预后：梅奥诊所经验的更新。
Am J Hematol. 2016 Jun;91(6):585-9. doi: 10.1002/ajh.24356. Epub 2016 Apr 13.
5
IL-6 in inflammation, immunity, and disease.白细胞介素-6在炎症、免疫及疾病中的作用
Cold Spring Harb Perspect Biol. 2014 Sep 4;6(10):a016295. doi: 10.1101/cshperspect.a016295.
6
Markedly upregulated serum interleukin-12 as a novel biomarker in POEMS syndrome.显著上调的血清白细胞介素-12 作为 POEMS 综合征的新型生物标志物。
Neurology. 2012 Aug 7;79(6):575-82. doi: 10.1212/WNL.0b013e318263c42b. Epub 2012 Jul 25.
7
Long-term outcomes after autologous stem cell transplantation for patients with POEMS syndrome (osteosclerotic myeloma): a single-center experience.POEMS 综合征（硬化性骨髓瘤）患者自体干细胞移植后的长期结果：单中心经验。
Blood. 2012 Jul 5;120(1):56-62. doi: 10.1182/blood-2012-04-423178. Epub 2012 May 18.
8
The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome.血浆血管内皮生长因子水平在 POEMS 综合征患者的诊断和随访中的应用。
Blood. 2011 Oct 27;118(17):4663-5. doi: 10.1182/blood-2011-06-362392. Epub 2011 Aug 31.
9
Increased hepatic and circulating interleukin-6 levels in human nonalcoholic steatohepatitis.人类非酒精性脂肪性肝炎中肝脏和循环中白细胞介素-6水平升高。
Am J Gastroenterol. 2008 Jun;103(6):1372-9. doi: 10.1111/j.1572-0241.2007.01774.x. Epub 2008 May 28.
10
Gene expression patterns in hepatic tissue and visceral adipose tissue of patients with non-alcoholic fatty liver disease.
Obes Surg. 2007 Aug;17(8):1111-8. doi: 10.1007/s11695-007-9187-y.