Ejdemyr Ivan, Sundqvist Robin, Bjureberg Johan, Birgegård Andreas, Jokinen Jussi, Levallius Johanna, Gilbert Kirsten, Sjögren Magnus
Department of Clinical Sciences, Umeå University, Umeå, Sweden.
National Specialized Medical Care for Eating Disorders, Region Västernorrland, Sundsvall, Sweden.
Eat Disord. 2025 Jul 11:1-19. doi: 10.1080/10640266.2025.2524215.
Anorexia nervosa (AN) is a serious health condition with insufficient treatment options. Radically Open Dialectical Behavior Therapy (RO-DBT) offers a new treatment approach targeting maladaptive overcontrol, a proposed underlying mechanism in AN. This study evaluated the feasibility, acceptability, and the preliminary efficacy of a 32-week standard RO-DBT intervention for individuals with AN in an outpatient setting. Twenty-three participants with AN (median age 20 years; median illness duration 5 years; 95.7% female) were included. Feasibility was demonstrated by a high retention rate (83%) and satisfactory completion of outcome measures, while acceptability was demonstrated by high treatment satisfaction. Participation in RO-DBT was associated with significant reductions in eating disorder psychopathology (, Cohen's = 0.90), significant increase in BMI (, Cohen's = 0.74), and increased use of the emotion regulation strategy cognitive reappraisal (, Cohen's = 0.70). These findings suggest that RO-DBT is a feasible, acceptable, and potentially effective treatment for AN.
神经性厌食症（AN）是一种治疗选择有限的严重健康状况。彻底开放辩证行为疗法（RO-DBT）提供了一种针对适应不良的过度控制的新治疗方法，过度控制是AN中一种潜在的机制。本研究评估了在门诊环境中对AN患者进行为期32周的标准RO-DBT干预的可行性、可接受性和初步疗效。纳入了23名AN患者（年龄中位数20岁；病程中位数5年；95.7%为女性）。高保留率（83%）和结果测量的满意完成证明了可行性，而高治疗满意度证明了可接受性。参与RO-DBT与饮食失调精神病理学显著降低（，科恩d = 0.90）、BMI显著增加（，科恩d = 0.74）以及情绪调节策略认知重评的使用增加（，科恩d = 0.70）相关。这些发现表明，RO-DBT是一种对AN可行、可接受且可能有效的治疗方法。
