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未知原发灶头颈部癌的FAP导向成像与治疗

FAP-Directed Imaging and Therapy in Head and Neck Cancer of Unknown Primary.

作者信息

Kunte Sophie C, Sheikh Gabriel T, Giesel Frederik L, Canis Martin, Werner Rudolf A

机构信息

Department of Nuclear Medicine, LMU University Hospital, LMU Munich, 81377 Munich, Germany.

Bavarian Cancer Research Center (BZKF), Partner Site Munich, 81377 Munich, Germany.

出版信息

Cancers (Basel). 2025 Jun 30;17(13):2205. doi: 10.3390/cancers17132205.

DOI:10.3390/cancers17132205
PMID:40647503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12249064/
Abstract

Head and neck cancer encompasses a diverse group of malignancies arising from various anatomical subsites, e [...].

摘要

头颈癌包括一组源自不同解剖亚部位的多种恶性肿瘤，如……

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6204/12249064/a50659e50bc7/cancers-17-02205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6204/12249064/a50659e50bc7/cancers-17-02205-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6204/12249064/a50659e50bc7/cancers-17-02205-g001.jpg

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本文引用的文献

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Imaging of Tumor Stroma Using Ga-FAPI PET/CT to Improve Diagnostic Accuracy of Primary Tumors in Head and Neck Cancer of Unknown Primary: A Comparative Imaging Trial.基于 Ga-FAPI PET/CT 的肿瘤基质成像提高原发灶不明头颈部鳞癌的诊断准确性：一项比较影像学试验
J Nucl Med. 2024 Mar 1;65(3):365-371. doi: 10.2967/jnumed.123.266556.
2
Development of FAPI Tetramers to Improve Tumor Uptake and Efficacy of FAPI Radioligand Therapy.开发 FAPI 四聚体以提高 FAPI 放射性配体治疗的肿瘤摄取和疗效。
J Nucl Med. 2023 Sep;64(9):1449-1455. doi: 10.2967/jnumed.123.265599. Epub 2023 Jun 15.
3
Fibroblast activation protein-targeted radionuclide therapy: background, opportunities, and challenges of first (pre)clinical studies.
成纤维细胞激活蛋白靶向放射性核素治疗：首次（临床前）研究的背景、机遇和挑战。
Eur J Nucl Med Mol Imaging. 2023 Jun;50(7):1906-1918. doi: 10.1007/s00259-023-06144-0. Epub 2023 Feb 23.
4
Head-to-Head Comparison of [ Ga]Ga-FAPI-46-PET/CT and [F]F-FDG-PET/CT for Radiotherapy Planning in Head and Neck Cancer.头对头比较[Ga]Ga-FAPI-46-PET/CT 和 [F]F-FDG-PET/CT 对头颈部癌症放疗计划的作用。
Mol Imaging Biol. 2022 Dec;24(6):986-994. doi: 10.1007/s11307-022-01749-7. Epub 2022 Jun 30.
5
Hypoxia in relationship to tumor volume using hypoxia PET-imaging in head & neck cancer - A scoping review.使用正电子发射断层扫描（PET）成像技术在头颈癌中研究缺氧与肿瘤体积的关系——一项范围综述
Clin Transl Radiat Oncol. 2022 Jun 15;36:40-46. doi: 10.1016/j.ctro.2022.06.004. eCollection 2022 Sep.
6
Accurate preoperative staging with [Ga]Ga-FAPI PET/CT for patients with oral squamous cell carcinoma: a comparison to 2-[F]FDG PET/CT.[Ga]Ga-FAPI PET/CT 对口腔鳞状细胞癌患者进行准确术前分期：与 2-[F]FDG PET/CT 的比较。
Eur Radiol. 2022 Sep;32(9):6070-6079. doi: 10.1007/s00330-022-08686-7. Epub 2022 Mar 30.
7
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J Nucl Med. 2022 Jun;63(6):875-881. doi: 10.2967/jnumed.121.262790. Epub 2021 Sep 30.