超越身体残疾：多发性硬化症患者生活质量中的社会认知挑战。
Beyond Physical Disability: The Social Cognition Challenges in Quality of Life Among Multiple Sclerosis Patients.
作者信息
Doskas Triantafyllos, Spiliopoulos Kanellos C, Kormas Constantinos, Kokkotis Christos, Dekavallas Liberis, Tsiakiri Anna, Christidi Foteini, Vavougios George D, Tsiptsios Dimitrios, Serdari Aspasia, Grigoriadis Nikolaos, Iliopoulos Ioannis, Vadikolias Konstantinos
机构信息
Department of Neurology, Athens Naval Hospital, 115 21 Athens, Greece.
Department of Neurology, Medical School, Democritus University of Thrace, 681 00 Alexandroupolis, Greece.
出版信息
Healthcare (Basel). 2025 Jul 4;13(13):1611. doi: 10.3390/healthcare13131611.
BACKGROUND/OBJECTIVES: Social cognition impairment is common in multiple sclerosis (MS) and could implicate the well-being of patients by promoting difficulties in social interactions. This study investigated the relationship between social cognition and quality of life (QoL) in patients with MS (PwMSs).
METHODS
In total, 100 PwMSs, enrolled as per distinct criteria, underwent neuropsychological assessment using validated questionnaires and scales. To assess QoL, Multiple Sclerosis Quality of Life-54 (MSQOL-54) questionnaires, both physical and mental, were utilized. The components of social cognition were evaluated using the Reading the Mind in the Eyes Test (RMET) and the Faux Pas task. The type of MS and years since diagnosis were also recorded.
RESULTS
The RMET score (β = 0.336; = 0.001) and years since diagnosis (β = -0.225; = 0.017) emerged as significant predictors of physical QoL, whereas the Faux Pas score did not significantly predict MSQOL-54_PHYSICAL scores ( = 0.451). Both Faux Pas (β = 0.247; = 0.015) and RMET scores (β = 0.221; = 0.028) showed a positive association with MSQOL-54_MENTAL scores. The years since diagnosis did not significantly predict the mental component of QoL ( = 0.635).
CONCLUSIONS
Social cognition deficits are crucial for the social functioning of patients with MS, inevitably affecting both physical and mental aspects of QoL.
背景/目的：社会认知障碍在多发性硬化症（MS）中很常见，可能会因导致社交互动困难而影响患者的幸福感。本研究调查了MS患者（PwMSs）的社会认知与生活质量（QoL）之间的关系。
方法
总共100名符合不同标准入选的PwMSs使用经过验证的问卷和量表进行了神经心理学评估。为评估生活质量，使用了多发性硬化症生活质量-54（MSQOL-54）问卷的身体和心理部分。使用“读心术”测试（RMET）和失言任务评估社会认知的组成部分。还记录了MS的类型和诊断后的年限。
结果
RMET得分（β = 0.336；P = 0.001）和诊断后的年限（β = -0.225；P = 0.017）是身体生活质量的重要预测因素，而失言任务得分并未显著预测MSQOL-54身体部分得分（P = 0.451）。失言任务得分（β = 0.247；P = 0.015）和RMET得分（β = 0.221；P = 0.028）均与MSQOL-54心理部分得分呈正相关。诊断后的年限并未显著预测生活质量的心理部分（P = 0.635）。
结论
社会认知缺陷对MS患者的社交功能至关重要，不可避免地会影响生活质量的身体和心理方面。
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