Chorti Angeliki, Pliakos Ioannis, Moysidis Moysis, Smprini Aikaterini, Bakkar Sohail, Papavramidis Theodossis
Propaedeutic Department of Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, 54636 Thessaloniki, Greece.
Department of Minimal Invasive Endocrine Surgery, Euromedica Kyanos Stavros, 54454 Thessaloniki, Greece.
J Clin Med. 2025 Jun 21;14(13):4418. doi: 10.3390/jcm14134418.
Postoperative hypoparathyroidism is a common complication of thyroid surgery. Sunlight is a natural source of ultraviolet B (UVB) radiation, which facilitates the synthesis of vitamin D3 in the skin. Inadequate sunlight exposure has been linked to vitamin D deficiency, potentially exacerbating the risk of hypocalcemia in patients undergoing thyroid surgery. The aim of the present study is to evaluate the effect of sunshine levels on postoperative hypoparathyroidism. We retrospectively evaluated patients that underwent total thyroidectomies at two different centers (Thessaloniki and Rhodes) by the same surgical team from 2021 to 2023 in terms of postoperative hypoparathyroidism. We compared the sunshine levels at each center the year before surgery and correlated them with postoperative levels of parathyroid hormone, serum ionized calcium, and phosphorus. One-hundred twenty patients (Group Thessaloniki = 60 patients, Group Rhodes = 60 patients) who were matched for demographic characteristics and type of thyroid disease and surgery were enrolled in our study. The sunshine levels were different between the two centers (Rhodes > Thessaloniki, < 0.001). It was found that sunshine levels affect preoperative serum ionized calcium ( = 0.002) and postoperative parathyroid hormone levels ( = 0.025). Sunlight exposure levels may play a crucial role in preventing postoperative hypoparathyroidism. Patients living in locations with higher sunshine levels may have lower rates of postoperative hypoparathyroidism.
术后甲状旁腺功能减退是甲状腺手术常见的并发症。阳光是紫外线B（UVB）辐射的天然来源，可促进皮肤中维生素D3的合成。阳光照射不足与维生素D缺乏有关，这可能会增加甲状腺手术患者发生低钙血症的风险。本研究的目的是评估日照水平对术后甲状旁腺功能减退的影响。我们回顾性评估了2021年至2023年在两个不同中心（塞萨洛尼基和罗德岛）由同一手术团队进行全甲状腺切除术的患者的术后甲状旁腺功能减退情况。我们比较了每个中心手术前一年的日照水平，并将其与术后甲状旁腺激素、血清离子钙和磷水平进行关联。120名患者（塞萨洛尼基组 = 60名患者，罗德岛组 = 60名患者）纳入我们的研究，这些患者在人口统计学特征、甲状腺疾病类型和手术方面相匹配。两个中心的日照水平不同（罗德岛 > 塞萨洛尼基，< 0.001）。研究发现日照水平影响术前血清离子钙（ = 0.002）和术后甲状旁腺激素水平（ = 0.025）。日照水平可能在预防术后甲状旁腺功能减退中起关键作用。生活在日照水平较高地区的患者术后甲状旁腺功能减退的发生率可能较低。
