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德国四家非大学医院的多中心肾脏药剂师小组——为肾功能损害患者提供药学服务

Multicenter Renal Pharmacist Group-Pharmaceutical Care for Patients with Renal Impairment at Four Non-University Hospitals in Germany.

作者信息

Seiberth Sarah, Bayerlein Katrin, Gerke Ann-Kristin, Ihbe-Heffinger Angela, Schobel Hans-Paul, Rudolph Jana, Leuschner Sarah, Müller Philipp, Richling Ina, Owandner Boris, Schmidt-Schnaubelt Tanja, Sieg Meike, Albus Larissa, von Ameln-Mayerhofer Andreas, Strobach Dorothea

机构信息

Doctoral Program Clinical Pharmacy, University Hospital of the Ludwig-Maximilians-University, 81377 Munich, Germany.

Hospital Pharmacy and Division of Nephrology, Starnberg Hospital, Academic Teaching Hospital of LMU, 82319 Starnberg, Germany.

出版信息

J Clin Med. 2025 Jun 26;14(13):4530. doi: 10.3390/jcm14134530.

Abstract

The project 'Multicenter Renal Pharmacist Group-Implementation of Pharmaceutical Care for Patients with Renal Impairment at four Non-University Hospitals in Germany' started in the beginning of 2020 with the goal to establish high-quality pharmaceutical care to improve patient safety for hospitalized patients with renal impairment at German non-university hospitals. Pharmaceutical service quality should be optimized by intense and effective intraprofessional collaboration within the network. Over a period of two years (2020-2022), we implemented renal pharmacists (RPs) for patients with renal impairment (RI) at four non-university hospitals in Germany (Starnberg Hospital, Rudolf Virchow Hospital Glauchau, Catholic Hospital in the Märkisch District (KKiMK), and Hospital Sindelfingen-Boeblingen). The RPs conducted medication analyses identifying renal-drug-related problems (rDRPs) two to five days a week. The rDRPs, including recommendations to solve them, were forwarded to the attending physicians via written consultations or personally during ward rounds. The RPs were mentored by a renal pharmacist expert from LMU Munich and formed a multicentered team with close collaboration. Data about the RP service were collected and were retrospectively evaluated. During the two-year project period, a total of 3924 patients from various disciplines were visited across all four locations. In total, 1425 patients (36.3%; with a range from 22.7 to 56.4% between hospitals) received one or more interventions by RPs concerning 2454 rDRPs (a median of one to three rDRPs per patient). In cooperation with the physicians, 77.6 to 88.2% of the rDRPs were solved. The most common causes were 'dosage too high' and 'contraindication'. The implementation of pharmaceutical care for patients with renal impairment at four non-university hospitals in Germany increased appropriate prescribing by physicians. The multicenter team proved to be an excellent support for the newly established services.

摘要

“多中心肾脏药剂师小组——德国四家非大学医院对肾功能损害患者实施药学服务”项目于2020年初启动,目标是在德国非大学医院为住院肾功能损害患者建立高质量药学服务,以提高患者安全性。通过网络内密切且有效的专业内协作来优化药学服务质量。在两年时间(2020 - 2022年)里,我们在德国四家非大学医院(施塔恩贝格医院、格劳乔的鲁道夫·菲尔绍医院、马尔基施地区天主教医院(KKiMK)以及辛德芬根 - 伯布林根医院)为肾功能损害(RI)患者配备了肾脏药剂师(RP)。肾脏药剂师每周两到五天进行用药分析,识别与肾脏药物相关的问题(rDRP)。这些rDRP以及解决建议通过书面会诊或在查房时亲自传达给主治医生。肾脏药剂师由慕尼黑大学路德维希 - 马克西米利安大学的一名肾脏药剂师专家指导,并组成了一个紧密协作的多中心团队。收集了关于肾脏药剂师服务的数据并进行回顾性评估。在为期两年的项目期间,四个地点共诊治了来自各个学科的3924名患者。总计1425名患者(36.3%;各医院之间的范围为22.7%至56.4%)接受了肾脏药剂师针对2454个rDRP的一项或多项干预(每位患者的rDRP中位数为一至三个)。与医生合作,77.6%至88.2%的rDRP得到了解决。最常见的原因是“剂量过高”和“禁忌症”。在德国四家非大学医院为肾功能损害患者实施药学服务提高了医生的合理用药水平。多中心团队被证明是对新建立服务的有力支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6659/12249759/6762ab56a2ca/jcm-14-04530-g001.jpg

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