Türk Çağlar, Sevgi Umut Tan, Bahadır Sinan, Çamlar Mahmut, Özer Füsun
Department of Neurosurgery, University of Health Sciences, Izmir City Hospital, Izmir 35540, Turkey.
Department of Neurosurgery, Faculty of Medicine, Baskent University, Ankara 06790, Turkey.
J Clin Med. 2025 Jul 2;14(13):4674. doi: 10.3390/jcm14134674.
: We aimed to review pediatric patients who underwent surgical treatment for posterior fossa tumors and to share our experience with the various types of dural grafts used in these patients. : We carried out a retrospective study on pediatric patients who received surgical treatment for posterior fossa tumors and underwent duraplasty using either an autograft or a xenograft from January 2018 to December 2022. Data were gathered from patients' medical records, encompassing demographic details. Additional information included tumor locations and the extent of resection. Factors such as postoperative complications like meningitis, pseudo-meningocele, and hydrocephalus were also noted. : Our cohort included 50 patients, 13 of whom underwent surgeries with autografts and 37 had xenografts. The patients' tumors were in various areas, including intraventricular or those extending into the ventricle (31) and intracerebellar (17) and extra-axial (2) cases. Subtotal resection occurred in 8 cases, near-total resection in 9, and gross-total resection in 33. Postoperatively, meningitis occurred in 12 patients, pseudo-meningocele in 13, and hydrocephalus in 10, with 9 requiring V/P placement. : In conclusion, techniques for dural closure hold great significance in neurosurgery, particularly during pediatric posterior fossa surgeries. Although the modest size of the autograft cohort limited statistical power, our epidural onlay fascia lata autograft produced fewer postoperative complications than the bovine xenograft and achieved outcomes comparable to those reported for watertight closure.
我们旨在回顾接受后颅窝肿瘤手术治疗的儿科患者，并分享我们在这些患者中使用的各种硬脑膜移植物的经验。我们对2018年1月至2022年12月期间接受后颅窝肿瘤手术治疗并使用自体移植物或异种移植物进行硬脑膜成形术的儿科患者进行了一项回顾性研究。数据从患者的病历中收集，包括人口统计学细节。其他信息包括肿瘤位置和切除范围。还记录了术后并发症，如脑膜炎、假性脑膜膨出和脑积水等因素。我们的队列包括50名患者，其中13名接受了自体移植物手术，37名接受了异种移植物手术。患者的肿瘤位于不同区域，包括脑室内或延伸至脑室的肿瘤（31例）、小脑内肿瘤（17例）和轴外肿瘤（2例）。8例为次全切除，9例为近全切除，33例为全切除。术后，12例患者发生脑膜炎，13例发生假性脑膜膨出，10例发生脑积水，9例需要进行脑室腹腔分流术。总之，硬脑膜闭合技术在神经外科手术中具有重要意义，尤其是在儿科后颅窝手术中。尽管自体移植物队列规模较小限制了统计效力，但我们的硬膜外阔筋膜自体移植物术后并发症比牛异种移植物少，且取得了与水密闭合报道相当的结果。
