Howard L J, Beckerman A H
Drug Nutr Interact. 1985;3(4):191-6.
While the term "drug-nutrient interactions" tends to conjure up a concept of an adverse combination, such as anticonvulsants impairing folate metabolism or alcohol blocking active thiamine absorption, there are situations in which a drug and nutrient can act in a complementary manner, to correct a metabolic defect. This case history illustrates such a positive interaction of glucocorticoids and L-carnitine supplements improving muscle function in a patient with myopathic carnitine deficiency.
虽然“药物-营养相互作用”一词往往会让人联想到不良组合的概念，比如抗惊厥药损害叶酸代谢或酒精阻碍活性硫胺素吸收，但在某些情况下，药物和营养物质可以以互补的方式发挥作用，以纠正代谢缺陷。本病例史说明了糖皮质激素与L-肉碱补充剂之间的这种积极相互作用，可改善患有肌病性肉碱缺乏症患者的肌肉功能。
