Wu Fuyong, Chen Long, Yu Mei, Zhao Liang, Jiang Lu, Shi Tianzhu, Guo Ju, Zheng Huayan, Wang Ruixiao, Liao Mingrui
Department of Brewing Engineering, Moutai Institute, Renhuai 564500, China.
Key Laboratory of Macrocycle and Supramolecular Chemistry of Guizhou Province, Guiyang 550025, China.
Molecules. 2025 Jun 30;30(13):2815. doi: 10.3390/molecules30132815.
Rationally designing and synthesizing chemosensors capable of simultaneously detecting both anions and cations via water content modulation is challenging. In this study, we synthesized and characterized a novel triazine calixarene derivative-based iodide and copper ion-selective fluorescent "turn-off" sensor. This dual-channeled fluorescent probe is able to recognize Cu and I ions simultaneously in aqueous systems. The fluorescent sensor was synthesized by displacement reaction of acridine with 1, 3-bis (dichloro-mono-triazinoxy) benzene in acetonitrile. Mass spectrometry (MS), UV-vis, and fluorescence spectra were acquired to characterize the fluorescence response of to different cations and anions, while infrared (IR) spectroscopy and isothermal titration calorimetry (ITC) were employed to study the underlying selectivity mechanism of to Cu and I. In detail, displayed extremely high sensitivity to Cu with over 80% fluorescence decrement caused by the paramagnetic nature of Cu in the aqueous media. The reversible fluorescence response to Cu and the responses to Cu in the solution of other potential interferent cations, such as Li, Na, K, Ca, Cd, Zn, Sr, Ni, Co were also investigated. Probe also exhibited very good fluorescence selectivity to iodide ions under various anion (F, Cl, Br, NO, HSO, ClO, PF, AcO, HPO) interferences. In addition to the fluorescent response to I, showed a highly selective naked-eye-detectable color change from colorless to yellow with the other tested anions.
通过调节含水量来合理设计和合成能够同时检测阴离子和阳离子的化学传感器具有挑战性。在本研究中，我们合成并表征了一种基于新型三嗪杯芳烃衍生物的碘化物和铜离子选择性荧光“关闭”传感器。这种双通道荧光探针能够在水性体系中同时识别铜离子和碘离子。该荧光传感器是通过吖啶与1,3-双（二氯-单-三嗪氧基）苯在乙腈中发生置换反应合成的。采用质谱（MS）、紫外可见光谱和荧光光谱来表征其对不同阳离子和阴离子的荧光响应，同时利用红外（IR）光谱和等温滴定量热法（ITC）研究其对铜离子和碘离子的潜在选择性机制。具体而言，由于铜离子在水性介质中的顺磁性，该传感器对铜离子表现出极高的灵敏度，荧光衰减超过80%。还研究了其对铜离子的可逆荧光响应以及在其他潜在干扰阳离子（如锂离子、钠离子、钾离子、钙离子、镉离子、锌离子、锶离子、镍离子、钴离子）溶液中对铜离子的响应。在各种阴离子（氟离子、氯离子、溴离子、硝酸根离子、硫酸氢根离子、高氯酸根离子、磷酸根离子、醋酸根离子、磷酸氢根离子）干扰下，探针 对碘离子也表现出非常好的荧光选择性。除了对碘离子的荧光响应外，与其他测试阴离子相比， 还表现出从无色到黄色的高选择性肉眼可检测颜色变化。
