Ophoff Gregory, Bellemans Johan, Ascani Daniele, Taylan Orçun, Scheys Lennart, Pandit Hemant, Peersman Geert
ZAS Cadix Antwerpen, Antwerp, Belgium.
University of Antwerp, Antwerp, Belgium.
Arch Orthop Trauma Surg. 2025 Jul 12;145(1):369. doi: 10.1007/s00402-025-05984-9.
Introduction This study investigates the elongation patterns of native knee collateral ligaments across various coronal plane alignment phenotypes (CPAK classification), aiming to refine soft tissue balancing in Total Knee Arthroplasty (TKA).
Materials and methods In this cross-sectional study, 84 patients were analyzed prior to undergoing TKA using a computer-assisted surgery (CAS) system. CPAK types were determined using pre-operative standing full-leg radiographs. The CAS system facilitated real-time tracking of the native medial (MCL) and lateral (LCL) collateral ligament elongation throughout passive knee motion. Data were normalized and analyzed using a linear mixed model to assess the impact of knee alignment on ligament elongation, with ANOVA and Fisher's LSD method applied at a 95% confidence level.
Results A significant correlation was observed between aHKA and MCL length changes during deep flexion (90°-110°), with the MCL shortening in valgus-aligned knees and lengthening in varus/neutral knees. CPAK III (valgus knees with high JLO) showed significantly more MCL shortening than CPAK I, II, and IV at 90° flexion (p < 0.05). Knees with similar aHKA values exhibited comparable MCL behavior. Across all CPAK types, the LCL displayed a consistent pattern of progressive loosening with flexion. Valgus knees, particularly CPAK III, demonstrated a significantly tighter LCL in full extension compared to other types (p < 0.05). No significant effect of aHKA or JLO on LCL behavior was found.
Conclusion This study demonstrates that MCL and LCL elongation patterns are phenotype-dependent. While the LCL consistently loosens with flexion across types, MCL behavior varies significantly with coronal alignment. These findings suggest that alignment-based ligament behavior must be considered for optimal soft tissue balance and support a shift toward personalized TKA strategies aimed at replicating native knee kinematics.
本研究调查了不同冠状面排列表型(CPAK分类)下天然膝关节侧副韧带的伸长模式,旨在优化全膝关节置换术(TKA)中的软组织平衡。
在这项横断面研究中,使用计算机辅助手术(CAS)系统对84例即将接受TKA的患者进行了分析。使用术前站立位全腿X线片确定CPAK类型。CAS系统有助于在膝关节被动运动过程中实时跟踪天然内侧(MCL)和外侧(LCL)副韧带的伸长情况。数据进行归一化处理,并使用线性混合模型进行分析,以评估膝关节排列对韧带伸长的影响,在95%置信水平下应用方差分析和Fisher最小显著差异法。
观察到在深度屈曲(90°-110°)期间,aHKA与MCL长度变化之间存在显著相关性,外翻排列的膝关节中MCL缩短,内翻/中立膝关节中MCL延长。CPAK III型(高JLO的外翻膝关节)在90°屈曲时MCL缩短明显多于CPAK I、II和IV型(p < 0.05)。具有相似aHKA值的膝关节表现出可比的MCL行为。在所有CPAK类型中,LCL随着屈曲呈现出一致的逐渐松弛模式。与其他类型相比,外翻膝关节,尤其是CPAK III型,在完全伸展时LCL明显更紧(p < 0.05)。未发现aHKA或JLO对LCL行为有显著影响。
本研究表明MCL和LCL的伸长模式取决于表型。虽然LCL在各类型中均随着屈曲持续松弛,但MCL行为随冠状面排列变化显著。这些发现表明,为实现最佳软组织平衡,必须考虑基于排列的韧带行为,并支持向旨在复制天然膝关节运动学的个性化TKA策略转变。