Bao Mingqiu, Huang Xinyu, Hao Yakai, Chen Huijin, Yue Ruirui, Xu Jingkun, Duan Xuemin
Jiangxi Provincial Key Laboratory of Flexible Electronics, College of Chemistry and Chemical Engineering, Jiangxi Science and Technology Normal University, Nanchang, 330013, China.
College of Life Science, Jiangxi Science and Technology Normal University, Nanchang, 330013, China.
Mikrochim Acta. 2025 Jul 12;192(8):499. doi: 10.1007/s00604-025-07354-z.
Ractopamine (RAC), illegally used in swine feed to promote lean muscle growth, seriously endangers human health (particularly children's development), necessitating rapid and accurate monitoring of its residues in pork and derived products. In this work, the well-structured gold/poly(3,4-ethylenedioxythiophene) nanowires (Au/PEDOT NWs) were facilely synthesized via interfacial polymerization, which enabled the uniform loading of Au nanoparticles (Au NPs) on/in cross-linked PEDOT NWs. The component, structure, and morphology of Au/PEDOT NWs were confirmed by series of physical characterization. The Au/PEDOT NWs were used to modify the electrode to fabricate a concise RAC sensing platform, which provides outstanding sensing properties featuring a low detection limit (LOD) of 1.67 μM, wide linear response spanning from 10~200 μM, and a high sensitivity of 1.33 μA μM cm. Furthermore, by comparison with the detecting results of high-performance liquid chromatography (HPLC), this sensing platform achieved satisfactory recoveries for RAC detection in pork samples. The sensor represents a groundbreaking advancement for food safety by enabling rapid, ultrasensitive, and highly selective detection, providing technical support for on-site food safety detection, and promoting the widespread application of electrochemical sensing technique.
莱克多巴胺（RAC）被非法用于猪饲料中以促进瘦肉生长，严重危害人体健康（尤其是儿童发育），因此需要快速准确地监测其在猪肉及衍生产品中的残留量。在这项工作中，通过界面聚合轻松合成了结构良好的金/聚（3,4 - 乙撑二氧噻吩）纳米线（Au/PEDOT NWs），这使得金纳米颗粒（Au NPs）能够均匀地负载在交联的PEDOT NWs上/内。通过一系列物理表征证实了Au/PEDOT NWs的成分、结构和形态。Au/PEDOT NWs用于修饰电极以构建一个简洁的RAC传感平台，该平台具有出色的传感性能，检测限低至1.67 μM，线性响应范围宽，从10~200 μM，灵敏度高达1.33 μA μM cm。此外，通过与高效液相色谱（HPLC）的检测结果比较，该传感平台在猪肉样品中RAC检测方面实现了令人满意的回收率。该传感器通过实现快速、超灵敏和高选择性检测，为食品安全现场检测提供技术支持，并推动电化学传感技术的广泛应用，代表了食品安全领域的一项突破性进展。
