阿扎尔队列人群中的抑郁症与未经治疗的龋齿：一项横断面研究。
Depression and Untreated Dental Caries Among the Azar Cohort Population: A Cross-Sectional Study.
作者信息
Katebi Katayoun, Alamdari Saba Soleimani, Mahboobi Zeinab, Faramarzi Elnaz, Sharififard Nasrin
机构信息
Liver and Gastrointestinal Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran; Department of Oral and Maxillofacial Medicine, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Int Dent J. 2025 Jul 11;75(5):100885. doi: 10.1016/j.identj.2025.100885.
BACKGROUND
Dental caries and depression are prevalent worldwide. This study aimed to investigate the relationship between depression, the intake of anti-depressive medication, and the presence of untreated decayed teeth (DT) in the Azar cohort population.
METHODS
This cross-sectional study utilised data obtained from the Azar cohort study. The Azar cohort began in 2014 in Shabestar, northwest of Iran, encompassing 15,006 adults aged 35 to 70. Most of the data were collected through questionnaires and oral examinations. In the present study, individuals diagnosed with depression from the Azar Cohort were assessed with respect to the number of untreated DT. The participants were divided into three groups: individuals with depressive disorder who were using medication; individuals with depressive disorder who were not using medication; and a comparison group. The comparison group was selected from non-depressed participants of the Azar Cohort, a group matched by age and gender. Individuals with complete dentures were excluded. Modifiers were adjusted for using regression analysis RESULTS: Data for 1369 individuals in the depression group and 2813 individuals in the comparison group were analysed. The overall mean (SD) for DT was 2.5 ± 3.3. The regression models indicated a significant relationship between DT and depression (P < .001). Additionally, there was a significant positive relationship between DT and not receiving medication in the depressed group (P < .001).
CONCLUSION
A higher prevalence of DT was observed among individuals with depression, especially those not receiving medication. These findings highlight the urgent need for targeted oral health promotion initiatives specifically tailored to individuals suffering from depression.
背景
龋齿和抑郁症在全球范围内普遍存在。本研究旨在调查阿扎尔队列人群中抑郁症、抗抑郁药物的使用与未治疗龋齿（DT）的存在之间的关系。
方法
这项横断面研究利用了从阿扎尔队列研究中获得的数据。阿扎尔队列于2014年在伊朗西北部的沙贝斯塔开始，涵盖15006名年龄在35至70岁之间的成年人。大部分数据是通过问卷调查和口腔检查收集的。在本研究中，对阿扎尔队列中被诊断为抑郁症的个体的未治疗DT数量进行了评估。参与者被分为三组：正在使用药物的抑郁症患者；未使用药物的抑郁症患者；以及一个对照组。对照组从阿扎尔队列的非抑郁症参与者中选取，该组在年龄和性别上匹配。佩戴全口假牙的个体被排除。使用回归分析对修正因素进行了调整。结果：对抑郁症组的1369名个体和对照组的2813名个体的数据进行了分析。DT的总体平均值（标准差）为2.5±3.3。回归模型表明DT与抑郁症之间存在显著关系（P<.001）。此外，抑郁症组中DT与未接受药物治疗之间存在显著的正相关关系（P<.001）。
结论
在抑郁症患者中，尤其是未接受药物治疗的患者中，观察到DT的患病率较高。这些发现凸显了迫切需要针对抑郁症患者制定专门的针对性口腔健康促进举措。
Zotero 插件