Eghtesad Sareh, Mohammadi Zahra, Shayanrad Amaneh, Faramarzi Elnaz, Joukar Farahnaz, Hamzeh Behrooz, Farjam Mojtaba, Zare Sakhvidi Mohammad Javad, Miri-Monjar Mohammadreza, Moosazadeh Mahmood, Hakimi Hamid, Rahimi Kazerooni Salar, Cheraghian Bahman, Ahmadi Ali, Nejatizadeh Azim, Mohebbi Iraj, Pourfarzi Farhad, Roozafzai Farzin, Motamed-Gorji Nazgol, Montazeri Seyed Ali, Masoudi Sahar, Amin-Esmaeili Masoumeh, Danaie Navid, Mirhafez Seyed Reza, Hashemi Hasan, Poustchi Hossein, Malekzadeh Reza
Digestive Disease Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Liver and Pancreatobiliary Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Arch Iran Med. 2017 Nov 1;20(11):691-695.
In the past, communicable diseases caused the highest mortality in Iran. Improvements in socioeconomic status and living standards including access to safe drinking water, along with the inception of Health Houses in the 1980s, have changed disease patterns, decreasing the spread of and deaths from infectious and communicable diseases. The incidence and prevalence of non-communicable diseases (NCD), however, have now increased in Iran, accounting for nearly 80% of deaths and disabilities. Without interventions, NCD are predicted to impose a substantial human and economic burden in the next 2 decades. However, Iran's health system is not equipped with the necessary policies to combat this growth and must refocus and reform. Therefore, in the year 2013, the Ministry of Health and Medical Education funded a well-designed nationwide cohort study-Prospective Epidemiological Research Studies in IrAN (PERSIAN)-in order to assess the burden of NCD and investigate the risk factors associated with them in the different ethnicities and geographical areas of Iran. The PERSIAN Cohort, which aims to include 200000 participants, has 4 components: Adult (main), Birth, Youth and Elderly, which are being carried out in 22 different regions of Iran. Having an enormous dataset along with a biobank of blood, urine, hair and nail samples, the PERSIAN Cohort will serve as an important infrastructure for future implementation research and will provide the evidence needed for new healthcare policies in order to better control, manage and prevent NCD.
过去，传染病在伊朗造成的死亡率最高。社会经济地位和生活水平的改善，包括获得安全饮用水，以及20世纪80年代健康之家的设立，改变了疾病模式，减少了传染病和感染性疾病的传播及死亡人数。然而，伊朗非传染性疾病（NCD）的发病率和患病率目前有所上升，占死亡和残疾人数的近80%。如果不进行干预，预计未来20年非传染性疾病将带来巨大的人力和经济负担。然而，伊朗的卫生系统并未配备应对这种增长的必要政策，必须重新调整重点并进行改革。因此，2013年，卫生和医学教育部资助了一项精心设计的全国性队列研究——伊朗前瞻性流行病学研究（PERSIAN），以评估非传染性疾病的负担，并调查伊朗不同种族和地理区域中与之相关的风险因素。PERSIAN队列旨在纳入20万名参与者，有4个组成部分：成人（主要）、出生、青年和老年，研究在伊朗22个不同地区开展。PERSIAN队列拥有庞大的数据集以及血液、尿液、头发和指甲样本生物样本库，将作为未来实施研究的重要基础设施，并为新的医疗政策提供所需证据，以便更好地控制、管理和预防非传染性疾病。
