角膜内皮对荧光素通透性的重新评估。

A reevaluation of corneal endothelial permeability to fluorescein.

作者信息

Araie M, Maurice D M

出版信息

Exp Eye Res. 1985 Sep;41(3):383-90. doi: 10.1016/s0014-4835(85)80029-4.

Abstract

The permeability of the corneal endothelium and its aqueous-cornea distribution ratio were reevaluated in the rabbit eye. Both parameters were determined in an individual eye by applying the dye first by iontophoresis and then by intravitreal injection, which allows the influence of fluorescein glucuronide on the fluorophotometric measurements to be excluded. The corneal endothelial permeability coefficient was 5.13 +/- 1.64 X 10(-4) cm min-1, and the aqueous-cornea distribution ratio was 0.25 +/- 0.06 (mean +/- S.D., n = 11) on the average, and the former was considerably greater than the previous results, while the latter was considerably smaller.

摘要

在兔眼中重新评估了角膜内皮的通透性及其房水-角膜分布比。通过先离子导入法后玻璃体腔内注射染料的方式在单只眼睛中测定这两个参数，这样可以排除荧光素葡糖醛酸对荧光光度测量的影响。角膜内皮通透性系数平均为5.13±1.64×10⁻⁴ cm/min，房水-角膜分布比平均为0.25±0.06（均值±标准差，n = 11），前者显著大于先前的结果，而后者显著小于先前结果。