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柬埔寨东北部疟疾反应性监测与应对策略评估:一项混合方法研究。

Evaluating malaria reactive surveillance and response strategies in northeast Cambodia: a mixed-methods study.

作者信息

Siv Sovannaroth, Htike Win, Molyta Meach Monyth, Lynn Thet, Aye Tun Nilar, Agius Paul A, Fowkes Freya J I

机构信息

Disease Elimination Program, Burnet Institute, Melbourne, VIC, Australia.

Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia.

出版信息

Malar J. 2025 Jul 13;24(1):229. doi: 10.1186/s12936-025-05475-7.

Abstract

BACKGROUND

Cambodia aims to eliminate malaria latest by 2030 applying the 1-3-7 malaria reactive surveillance and response (RASR) strategy which involves malaria case notification, investigation and classification on the same day as diagnosis, reactive case detection within three days, and investigation and classification of new active focus within seven days of case notification. This study investigates the implementation of the RASR strategy in terms of its timeliness, facilitators and barriers, and acceptability for implementation, thereby providing recommendations to improve the strategy in the context of the national health system.

METHODS

A mixed-methods study of secondary data analysis of aggregated routine malaria datasets, and cross-sectional survey, in-depth interviews and focus group discussions with malaria programme stakeholders, frontline health workers and mobile and migrant populations was conducted in Ratanakiri and Stung Treng provinces. Quantitative and qualitative data were analysed descriptively and thematically.

RESULTS

In 2020 and 2022, 72% and 59% of malaria cases were notified and investigated within one day after diagnosis. Timeliness of reactive case detection was 89% and 45% in 2020 and 2022 respectively. Despite having challenges including minimal community participation in reactive case detection, poor mobile phone network coverage and road conditions, a heavy workload at the commune health centre level, inadequate surveillance technical knowledge among village malaria workers and insufficient budget to execute RASR, the existing RASR strategy was deemed acceptable among all levels of health personnels.

CONCLUSION

The RASR strategy implemented in northeast Cambodia was generally functioning well despite some challenges. To improve the RASR strategy to achieve 100% timeliness and progress towards malaria elimination in Cambodia, allocating sufficient budget, capacity building to frontline health workers and better community engagement strategies are required.

摘要

背景

柬埔寨旨在最迟在2030年消除疟疾,采用1-3-7疟疾反应性监测与应对(RASR)策略,该策略包括在诊断当天进行疟疾病例通报、调查和分类,在三天内进行反应性病例检测,以及在病例通报后七天内对新的活跃疫点进行调查和分类。本研究从及时性、促进因素和障碍以及实施的可接受性方面调查RASR策略的实施情况,从而为在国家卫生系统背景下改进该策略提供建议。

方法

在腊塔纳基里省和上丁省开展了一项混合方法研究,对汇总的常规疟疾数据集进行二次数据分析,并与疟疾项目利益相关者、一线卫生工作者以及流动和移民人群进行横断面调查、深入访谈和焦点小组讨论。对定量和定性数据进行描述性和主题性分析。

结果

在2020年和2022年,分别有72%和59%的疟疾病例在诊断后一天内得到通报和调查。2020年和2022年反应性病例检测的及时性分别为89%和45%。尽管存在一些挑战,包括社区在反应性病例检测中的参与度极低、手机网络覆盖和道路状况差、公社卫生中心层面工作量大、乡村疟疾防治人员的监测技术知识不足以及执行RASR的预算不足,但现有的RASR策略在各级卫生人员中被认为是可接受的。

结论

柬埔寨东北部实施的RASR策略尽管存在一些挑战,但总体运行良好。为改进RASR策略以实现100%的及时性并推动柬埔寨实现疟疾消除目标,需要分配足够的预算、对一线卫生工作者进行能力建设以及采取更好的社区参与策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26bf/12255966/52717d73c946/12936_2025_5475_Fig1_HTML.jpg

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