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症状性骶部塔尔洛夫囊肿强化神经根成形术疗效的预测因素分析

Analysis of predictive factors for the efficacy of reinforced radiculoplasty in symptomatic sacral Tarlov cysts.

作者信息

Zhu Jin, Li Ling, Wang Xizhu, Shi Liang, Su Yibing

机构信息

Department of Neurosurgery, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China.

出版信息

Neurosurg Rev. 2025 Jul 14;48(1):564. doi: 10.1007/s10143-025-03712-w.

DOI:10.1007/s10143-025-03712-w
PMID:40653586
Abstract

Reinforced radiculoplasty of the sacral nerve roots has been used in the treatment of symptomatic sacral Tarlov cysts (TCs). However, there is still insufficient evidence to support the effectiveness of this procedure in relieving pain, numbness, or bowel and bladder dysfunction in TC patients. In this single-center retrospective study, we reviewed data and conducted telephone follow-ups of 41 patients who underwent surgery between 2021 and 2023. Clinical characteristics-such as age, gender, follow-up duration, cyst length, number of cysts, side of cysts, number of nerves, preoperative selective nerve root block (SNRB), and pre- and postoperative symptoms-were collected and analyzed using binary logistic regression to identify potential predictors. A total of 41 patients were included in the study. Significant improvements were observed in pain and numbness across the entire patient group, the lateral side subgroup, and the no-SNRB subgroup, as well as in pain among female patients (P < 0.05). Among the 33 patients with preoperative pain, binary logistic regression analysis revealed that of age and preoperative visual analogue scale (VAS) scores were significantly associated with pain-free status (P < 0.05). However, no variables were found to be significantly associated with numbness relief (P > 0.05). In conclusion, reinforced radiculoplasty can significantly improve pain and numbness in patients with sacral TC. Older age and lower preoperative VAS scores are associated with a greater likelihood of achieving a pain-free outcome.

摘要

骶神经根强化成形术已被用于治疗有症状的骶部塔尔洛夫囊肿(TCs)。然而,仍缺乏足够的证据支持该手术在缓解TC患者疼痛、麻木或肠道及膀胱功能障碍方面的有效性。在这项单中心回顾性研究中,我们回顾了数据并对2021年至2023年间接受手术的41例患者进行了电话随访。收集了年龄、性别、随访时间、囊肿长度、囊肿数量、囊肿侧别、神经数量、术前选择性神经根阻滞(SNRB)以及术前和术后症状等临床特征,并使用二元逻辑回归进行分析以确定潜在预测因素。该研究共纳入41例患者。在整个患者组、外侧亚组和无SNRB亚组中,疼痛和麻木均有显著改善,女性患者的疼痛也有改善(P < 0.05)。在33例术前有疼痛的患者中,二元逻辑回归分析显示年龄和术前视觉模拟评分(VAS)与无痛状态显著相关(P < 0.05)。然而,未发现有变量与麻木缓解显著相关(P > 0.05)。总之,骶神经根强化成形术可显著改善骶部TC患者的疼痛和麻木。年龄较大和术前VAS评分较低与实现无痛结局的可能性更大相关。

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本文引用的文献

1
Microsurgical reinforced radiculoplasty for the treatment of postoperative recurrent sacral Tarlov cysts.显微外科强化神经根成形术治疗术后复发性骶部塔尔洛夫囊肿
Neurosurg Rev. 2025 Feb 19;48(1):248. doi: 10.1007/s10143-025-03405-4.
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Nerve Cuff Reconstruction for Sacral Duct Tarlov Cyst.神经袖重建治疗骶管蛛网膜囊肿。
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Operative Treatment of Tarlov Cysts - Outcomes and Predictors of Improvement after Surgery: A Series of 97 Consecutive Patients and a Systematic Review of Literature.
塔尔洛夫囊肿的手术治疗——手术效果及改善的预测因素:97例连续病例系列及文献系统综述
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Pain Pract. 2024 Mar;24(3):525-552. doi: 10.1111/papr.13317. Epub 2023 Nov 20.
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Management of Tarlov cysts: an uncommon but potentially serious spinal column disease-review of the literature and experience with over 1000 referrals.Tarlov 囊肿的治疗:一种少见但潜在严重的脊柱疾病——文献回顾及对 1000 余例转诊病例的诊治经验。
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Sacral Tarlov cysts: Neurophysiology abnormalities and correlation with pelvic sensory and visceral symptoms.骶骨 Tarlov 囊肿:神经生理学异常与盆腔感觉和内脏症状的相关性。
Eur J Neurol. 2023 Sep;30(9):2838-2848. doi: 10.1111/ene.15869. Epub 2023 Jun 13.
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Giant Tarlov Cyst presenting as pelvic mass: Often doing less is better.表现为盆腔肿块的巨大塔洛夫囊肿:通常少做(干预)更好。
Surg Neurol Int. 2023 Mar 24;14:95. doi: 10.25259/SNI_79_2023. eCollection 2023.
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Beijing Da Xue Xue Bao Yi Xue Ban. 2023 Feb 18;55(1):133-138. doi: 10.19723/j.issn.1671-167X.2023.01.020.
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J Neurosurg Spine. 2022 Jul 1;37(6):905-913. doi: 10.3171/2022.3.SPINE211437. Print 2022 Dec 1.