Abdi Delshad, Huttunen Jukka, Leinonen Ville, Savolainen Sakari, Danner Nils
Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Neurocenter, Neurosurgery, Kuopio University Hospital, Kuopio, Finland.
Global Spine J. 2025 Mar;15(2):1041-1048. doi: 10.1177/21925682231221538. Epub 2023 Dec 9.
A register-based retrospective series and a systematic review of literature.
Tarlov cysts are meningeal cysts typically found in the sacral region. They have a dualistic nature ranging from an incidental finding to a symptomatic pathology. There are no established treatment protocols and predictors of operative outcome. Therefore, we aimed to study the outcome of surgical treatment for Tarlov cysts and to characterize patient-, and treatment-related factors predicting outcomes.
A systematic review of previous literature was performed and a retrospective cohort of all patients operated on for Tarlov cysts at BLINDED between 1995 and 2020 was collected. Patient records were evaluated along with radiological images.
Ninety-seven consecutive patients were identified with follow-up data available for 96. Improvement of symptoms after surgery was observed in 76.0% of patients (excellent or good patient-reported outcome) and the complication rate was 17.5%. Sacral or lower back pain as a preoperative symptom was associated with improvement after surgery ( = .007), whereas previous lower back surgery was more common in patients who did not benefit from surgery ( = .034). No independent predictors of outcome were identified in a regression analysis.
This is the second-largest study on the treatment of Tarlov cysts ever published. Operative treatment in a selected patient population will likely produce improvement in the symptoms when balanced with the complication rate and profile of surgery. Preoperative lower back or sacral pain is a potential indicator for improvement after surgery.
基于登记的回顾性系列研究及文献系统综述。
塔尔洛夫囊肿是一种通常见于骶骨区域的脑脊膜囊肿。其具有二元性，从偶然发现到有症状的病变。目前尚无既定的治疗方案和手术结果预测指标。因此，我们旨在研究塔尔洛夫囊肿手术治疗的结果，并确定预测结果的患者相关因素和治疗相关因素。
对既往文献进行系统综述，并收集1995年至2020年期间在[机构名称未提及]接受塔尔洛夫囊肿手术的所有患者的回顾性队列。对患者记录及影像学图像进行评估。
共确定97例连续患者，其中96例有随访数据。76.0%的患者术后症状改善（患者报告的结果为优秀或良好），并发症发生率为17.5%。术前有骶骨或下背部疼痛症状与术后改善相关（P = 0.007），而既往接受过下背部手术在未从手术中获益的患者中更为常见（P = 0.034）。回归分析未发现结果的独立预测因素。
这是有史以来关于塔尔洛夫囊肿治疗的第二大研究。在选定的患者群体中进行手术治疗，在综合考虑并发症发生率和手术情况后，可能会改善症状。术前下背部或骶骨疼痛是术后改善的一个潜在指标。
