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搭载“宇宙-1514”生物卫星进行短期太空飞行后,孕鼠骨髓和脾脏中造血干细胞(CFUs)数量的变化。

Changes in the number of haemopoietic stem cells (CFUs) in bone marrow and spleens of pregnant rats after a short space flight onboard the Cosmos-1514 biosatellite.

作者信息

Vacek A, Serova L V, Rotkovská D, Mitchurina T V, Damaratskaya E I, Bartonícková A, Pryanishnikova O D, Khrushchov N G

出版信息

Folia Biol (Praha). 1985;31(5):361-5.

PMID:4065378
Abstract

After a 5-day stay in a state of weightlessness onboard a biosatellite Cosmos-1514 the pregnant rats exhibited a decrease in the number of haemopoietic stem cells (CFUs) in bone marrow and spleens on the recovery day after the space flight as compared to rats kept in the vivarium under usual conditions. The different changes in the concentration of CFUs in the bone marrow and spleens of flight and synchronous control rats indicate that the extent of the decrease in CFUs pool in the spleens of flight rats was significantly influenced by the action of non-specific flight factors.

摘要

在生物卫星“宇宙-1514”上处于失重状态5天后,与在正常条件下饲养在动物饲养室的大鼠相比,怀孕大鼠在太空飞行后的恢复日骨髓和脾脏中造血干细胞(CFU)数量减少。飞行大鼠和同步对照大鼠骨髓和脾脏中CFU浓度的不同变化表明,飞行大鼠脾脏中CFU池减少的程度受到非特异性飞行因素作用的显著影响。

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