Knychalska-Karwan Z, Pawlicki R
Folia Histochem Cytobiol. 1985;23(3):185-8.
The observations included the connective tissue laminae originating from samples of the buccal mucous membrane in leukoplakia. Following fixation and dehydration the materials were embedded in Epon 812, and the electronograms for the evaluation were obtained with the use of a Tesla BS 500 electron microscope. The macrophages were encountered close to the basal membrane in the proper lamina. The space between the basal cells and the macrophages was filled with the connective tissue matrix and numerous collagen fibres, as well as the fibroblast cells. Numerous mast cells, characterized by a specific activity, were noted. Additionally, the proper lamina contained few nerve fibres, usually nonmyelinated. The vascular bed was normal. The electronograms in leukoplakia revealed an active synthesis of the connective tissue matrix and collagen fibres. The marked activity of the mast cells was manifested by a high number of cells containing a relatively differentiated amount of granulation. This might be related to the chronic character of the disease. A significant activity of particular elements of the proper lamina, i.e. the cellular elements, collagen fibres and the connective tissue matrix appears to be characteristic of leukoplakia.
观察结果包括源自白斑颊黏膜样本的结缔组织板层。固定和脱水后，将材料包埋在Epon 812中，并使用特斯拉BS 500电子显微镜获得用于评估的电子显微照片。在固有层的基底膜附近发现了巨噬细胞。基底细胞和巨噬细胞之间的空间充满了结缔组织基质、大量胶原纤维以及成纤维细胞。观察到许多具有特定活性特征的肥大细胞。此外，固有层含有少量神经纤维，通常为无髓鞘的。血管床正常。白斑的电子显微照片显示结缔组织基质和胶原纤维的活跃合成。肥大细胞的显著活性表现为大量含有相对分化程度颗粒的细胞。这可能与该疾病的慢性特征有关。固有层特定成分，即细胞成分、胶原纤维和结缔组织基质的显著活性似乎是白斑的特征。
