Akbay T, Akbay C
Department of Prosthetic Dentistry, Gulhane Miliary Medical Academy and Faculty Etlik, Ankara, Turkey.
J Prosthet Dent. 1988 Jan;59(1):52-8. doi: 10.1016/0022-3913(88)90108-4.
An ultrastructural investigation was made to study the tissue changes occurring under complete dentures. Biopsy from 45 patient specimens were obtained from lesions of hard palate mucosa. Narrow intercellular space with less distinct bridges, loosely knit arrangement of tonofilaments, prominent endoplasmic reticulum, and vacuolar conformation of mitochondria were observed in the cells of epithelium. The underlying connective tissue was characterized by a preponderance of newly formed collagen fibers and numerous fibroblasts. Macrophages were located in the lamina propria and perivascular regions. Lymphocytes, neutrophils, and plasma cells were seen in moderate numbers. These cells, when present in clusters, should be considered as a component of the defense system.
进行了超微结构研究，以探讨全口义齿下发生的组织变化。从45例患者硬腭黏膜病变处获取活检标本。上皮细胞可见细胞间隙狭窄，桥粒不明显，张力丝排列疏松，内质网突出，线粒体呈空泡状。其下方的结缔组织以新形成的胶原纤维和大量成纤维细胞为主。巨噬细胞位于固有层和血管周围区域。可见中等数量的淋巴细胞、中性粒细胞和浆细胞。这些细胞若成群出现，应被视为防御系统的组成部分。
