Ndongo Sonfack Davaine Joel, Brunette-Clément Tristan, Olijnyk Leonardo, Gennari Antoine, Shédid Daniel, Yuh Sung-Joo
Faculty of Medicine, Laval University, Quebec, Qc, Canada.
Department of Neurosurgery, University of Montreal, Montreal, QC, Canada.
Can J Neurol Sci. 2025 Jul 14:1-11. doi: 10.1017/cjn.2025.10366.
Meningiomas are benign spinal arachnoid tumours, typically presenting as intradural extramedullary (IDEM) lesions that can compress the spinal cord and require surgical intervention. Minimally invasive surgery (MIS) techniques like mini-open, tubular and endoscopic approaches minimize tissue manipulation, reduce pain and accelerate recovery. This systematic review provides insights into current practices regarding MIS for cervical meningioma and presents a case series of eight patients with cervical meningioma effectively managed by MIS.
A comprehensive literature search was conducted across Embase, PubMed and Medline Ovid, focusing on MESH terms related to cervical vertebrae, nervous system neoplasms and minimally invasive surgical procedures. Risk of bias in retained studies was assessed using the Joanna Briggs Institute Critical Appraisal tools for case series and case reports. A narrative synthesis of our results is presented.
Nine studies with 15 patients undergoing MIS for cervical meningioma were included. Most tumours were at the craniospinal junction. Gross total resection (Simpson grade 2) was achieved in 14 cases, with no reported post-operative complications. The length of stay (LOS) ranged from 2 to 6 days, and no tumour recurrence was observed. Our case series of eight patients confirmed MIS benefits, including shorter operative times, comparable surgical outcomes, and the avoidance of spinal deformities requiring instrumentation.
In well-selected patients, MIS for cervical meningioma is a safe and effective procedure offering direct lateral access, minimal bony resection, limited soft tissue manipulation, and avoidance of cervical fusion, thereby minimizing post-operative complications and LOS.
脑膜瘤是良性脊髓蛛网膜肿瘤，通常表现为硬脊膜内髓外（IDEM）病变，可压迫脊髓，需要手术干预。诸如微型开放、管状和内镜手术等微创手术（MIS）技术可减少组织操作，减轻疼痛并加速康复。本系统评价深入探讨了目前关于颈椎脑膜瘤微创手术的实践情况，并介绍了一组通过微创手术有效治疗的8例颈椎脑膜瘤患者的病例系列。
在Embase、PubMed和Medline Ovid上进行了全面的文献检索，重点关注与颈椎、神经系统肿瘤和微创手术相关的医学主题词。使用乔安娜·布里格斯研究所病例系列和病例报告的关键评估工具评估纳入研究的偏倚风险。对我们的结果进行了叙述性综合分析。
纳入了9项研究，共15例接受颈椎脑膜瘤微创手术的患者。大多数肿瘤位于颅颈交界处。14例实现了全切除（辛普森2级），未报告术后并发症。住院时间为2至6天，未观察到肿瘤复发。我们的8例患者病例系列证实了微创手术的益处，包括手术时间更短、手术效果相当，以及避免了需要器械固定的脊柱畸形。
对于精心挑选的患者，颈椎脑膜瘤的微创手术是一种安全有效的手术方法，可提供直接外侧入路、最小限度的骨质切除、有限的软组织操作，并避免颈椎融合，从而将术后并发症和住院时间降至最低。
