Rantakallio P, von Wendt L
Dev Med Child Neurol. 1985 Oct;27(5):655-63. doi: 10.1111/j.1469-8749.1985.tb14138.x.
A birth cohort of 12,058 infants was followed up to 14 years of age. Cerebral palsy, epilepsy, severe hearing defects, mental retardation and educational subnormality all had a higher incidence among the 411 children with a low birthweight (less than 2500 g). 6 per cent of the total cohort had educational problems with or without some other neurological handicap, and there was a higher prevalence among low-birthweight infants. 1.5 per cent had a handicap but normal school performance. Children with birthweight 1500 to 2499 g had a significantly higher percentage of handicaps than those of heavier birthweight. All the neurological handicaps were more common among boys than girls, but only in mental subnormality was there a marked difference. Height at 14 years was significantly less among low-birthweight children.
对12058名婴儿的出生队列进行了随访,直至其14岁。在411名低体重(低于2500克)儿童中,脑瘫、癫痫、严重听力缺陷、智力迟钝和教育水平低于正常的发生率都更高。在整个队列中,6%的儿童有教育问题,无论是否伴有其他神经障碍,且低体重婴儿中的患病率更高。1.5%的儿童有残疾但学业成绩正常。出生体重在1500至2499克之间的儿童的残疾比例明显高于出生体重较重的儿童。所有神经障碍在男孩中比在女孩中更常见,但只有在智力低于正常方面存在显著差异。14岁时,低体重儿童的身高明显较低。