Hou Chengsu, Zhang Ye, Wang Yang
Department of Stomatology, Fengcheng Hospital of Fengxian District, Shanghai Ninth People's Hospital Fengcheng Branch Hospital, Shanghai, China.
Department of Oral and Maxillofacial Surgery, Zhongshan Hospital, School of Stomatology, Fudan University, Shanghai, China.
J Dent Sci. 2025 Jul;20(3):1899-1903. doi: 10.1016/j.jds.2025.03.004. Epub 2025 Mar 17.
BACKGROUND/PURPOSE: Salivary adenoid cystic carcinoma (SACC) affects the major salivary glands and minor salivary glands mainly within the oral cavity. The purpose of this study was to analyze the scientometric characteristics and research trends of SACC.
All the papers on SACC were comprehensively retrieved from the Scopus database. The years of publication were divided into before 2015 and 2015-2024 in the analysis of research trends.
There were 2406 papers on SACC, with total citations of 54,921 and the index of 97. Cancer surgery, radiotherapy, chemotherapy, cisplatin, doxorubicin, neck dissection, and combined modality therapy were the main keywords of treatment. The trend of clinical study on cell differentiation, doxorubicin, and fluorouracil has changed to clinical trial, cohort analysis, diagnostic imaging, positron emission tomography-computed tomography (PET-CT), intensity modulated radiation therapy, neck dissection, and surgical margin after 2015. The trend of laboratory investigation on cancer cell culture, cytology, protein S100, and flow cytometry has changed to epithelial mesenchymal transition, fluorescence in situ hybridization, gene fusion, microRNA, MYB, protein Myb, protein p63, and signal transduction after 2015.
This study for the first time elucidated the current scenario and scientometric characteristics of SACC, and would help in improving in reciprocal collaboration and provide helpful guidance for further research.
背景/目的：涎腺腺样囊性癌（SACC）主要累及口腔内的大涎腺和小涎腺。本研究旨在分析SACC的科学计量学特征和研究趋势。
从Scopus数据库全面检索所有关于SACC的论文。在研究趋势分析中，将发表年份分为2015年之前和2015 - 2024年。
共有2406篇关于SACC的论文，总被引次数为54921次，h指数为97。癌症手术、放疗、化疗、顺铂、阿霉素、颈清扫术和综合治疗模式是主要的治疗关键词。2015年后，关于细胞分化、阿霉素和氟尿嘧啶的临床研究趋势转变为临床试验、队列分析、诊断成像、正电子发射断层扫描 - 计算机断层扫描（PET - CT）、调强放射治疗、颈清扫术和手术切缘。2015年后，关于癌细胞培养、细胞学、蛋白质S100和流式细胞术的实验室研究趋势转变为上皮 - 间质转化、荧光原位杂交、基因融合、微小RNA、MYB、蛋白质Myb、蛋白质p63和信号转导。
本研究首次阐明了SACC的现状和科学计量学特征，有助于加强相互合作，并为进一步研究提供有益指导。
