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视神经脊髓炎谱系障碍:一例报告

Neuromyelitis Optica Spectrum Disorder: A Case Report.

作者信息

Karki Prakriti, Pahari Sagar, Neupane Nayan, Poudel Kushal, Asharaf Nehal

机构信息

Tairunnessa Memorial Medical College and Hospital, Gazipur, Bangladesh.

Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2024 Sep;62(277):602-604. doi: 10.31729/jnma.8748. Epub 2024 Sep 30.

Abstract

Neuromyelitis optica spectrum disorder also known as Devic's disease is an autoimmune condition where the body produces antibodies against Aquaporin-4 in the astrocytes. This affects the brain and spinal cord leading to numerous manifestations like paralysis, transverse myelitis, and optic neuritis. MRI and aquaporin-4 antibody (AQP4-IgG) are crucial for its diagnosis. Treatment of the acute stage involves plasma exchange and intravenous steroids. Steroids and immune modulators can do long-term management. This case highlights a 40-year-old woman who manifested a wide range of neurological symptoms, including paralysis and eyesight loss. She had blood testing, radiology, and a clinical evaluation to diagnose her condition. Neuromyelitis optica spectrum disorder was diagnosed in light of the investigations. This instance emphasizes the need for careful examination and consideration of any paralysis. To prevent patients from experiencing psychological, financial, or physical challenges, treating physicians should be vigilant for any findings related to conditions like neuromyelitis optica spectrum disorder.

摘要

视神经脊髓炎谱系障碍,也称为德维克氏病,是一种自身免疫性疾病,身体会产生针对星形胶质细胞中水通道蛋白4的抗体。这会影响大脑和脊髓,导致多种症状,如瘫痪、横贯性脊髓炎和视神经炎。磁共振成像(MRI)和水通道蛋白4抗体(AQP4-IgG)对其诊断至关重要。急性期的治疗包括血浆置换和静脉注射类固醇。类固醇和免疫调节剂可用于长期管理。该病例突出了一名40岁女性,她表现出广泛的神经症状,包括瘫痪和视力丧失。她接受了血液检测、放射学检查和临床评估以诊断病情。根据检查结果诊断为视神经脊髓炎谱系障碍。这个案例强调了对任何瘫痪情况进行仔细检查和考虑的必要性。为防止患者面临心理、经济或身体方面的挑战,治疗医生应对与视神经脊髓炎谱系障碍等病症相关的任何发现保持警惕。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b388/11665763/e0808d883cd9/JNMA-62-277-602-g1.jpg

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