Rashid Mohammed E
Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Kingdom of Saudi Arabia.
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1288-S1290. doi: 10.4103/jpbs.jpbs_240_25. Epub 2025 Jun 18.
Silver diamine fluoride (SDF) has emerged as an effective, noninvasive treatment for arresting dental caries. While its use has been extensively studied in pediatric populations, there is limited evidence regarding its effectiveness in adults.
This prospective study was conducted on 100 adult patients aged 25-60 years with active caries lesions in posterior teeth. Participants were randomly divided into two groups: the experimental group received a single application of 38% SDF, while the control group received standard fluoride varnish. Caries arrest was assessed using visual-tactile examination and scored using the International Caries Detection and Assessment System criteria at baseline, 1 month, and 6 months. Patient satisfaction and side effects were also documented. Statistical analysis was performed using paired -tests and Chi-square tests, with a significance level set at < 0.05.
After 6 months, 85% of caries lesions in the SDF group were arrested, compared to 45% in the fluoride varnish group ( < 0.001). Patient satisfaction scores were significantly higher in the SDF group, with a mean score of 4.7 compared to 3.5 in the control group. Minor side effects, such as temporary staining, were observed in 90% of SDF-treated teeth but were deemed acceptable by patients.
The application of 38% SDF is highly effective in arresting caries in adult patients and provides a promising, minimally invasive treatment option. Although tooth staining remains a common side effect, its clinical benefits outweigh aesthetic concerns, making it a valuable tool in caries management.
氟化亚锡已成为一种有效的龋齿非侵入性治疗方法。虽然其在儿科人群中的应用已得到广泛研究,但关于其在成人中的有效性的证据有限。
本前瞻性研究对100名年龄在25至60岁之间的后牙患有活动性龋损的成年患者进行。参与者被随机分为两组:实验组接受一次38%的氟化亚锡治疗,而对照组接受标准氟化物漆治疗。在基线、1个月和6个月时,使用视觉触觉检查评估龋齿进展情况,并根据国际龋齿检测和评估系统标准进行评分。还记录了患者满意度和副作用。使用配对t检验和卡方检验进行统计分析,显著性水平设定为<0.05。
6个月后,氟化亚锡组85%的龋损得到控制,而氟化物漆组为45%(<0.001)。氟化亚锡组患者满意度得分显著更高,平均得分为4.7,而对照组为3.5。在90%接受氟化亚锡治疗的牙齿中观察到轻微副作用,如暂时染色,但患者认为可以接受。
应用38%的氟化亚锡对成年患者的龋齿控制非常有效,并提供了一种有前景的微创治疗选择。虽然牙齿染色仍然是常见的副作用,但其临床益处超过了美观问题,使其成为龋齿管理中的一种有价值的工具。