• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Effectiveness of Silver Diamine Fluoride in Arresting Caries in Adult Patients.氟化亚锡对成年患者龋齿的防治效果。
J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1288-S1290. doi: 10.4103/jpbs.jpbs_240_25. Epub 2025 Jun 18.
2
Effectiveness of silver diamine fluoride application with atraumatic restorative treatment in arresting the progression of dental caries in children and adults: a systematic review and meta-analysis.氟化银氨联合非创伤性修复治疗对儿童和成人龋齿进展的抑制效果:一项系统评价和荟萃分析。
JBI Evid Synth. 2025 Jun 3. doi: 10.11124/JBIES-24-00299.
3
Topical silver diamine fluoride (SDF) for preventing and managing dental caries in children and adults.局部用氨丁三醇银(SDF)预防和治疗儿童及成人龋齿。
Cochrane Database Syst Rev. 2024 Nov 7;11(11):CD012718. doi: 10.1002/14651858.CD012718.pub2.
4
Comparative assessment of biocompatibility of various fluoride agents in cell culture.细胞培养中各种氟化物制剂生物相容性的比较评估。
BMC Oral Health. 2025 Jul 2;25(1):1009. doi: 10.1186/s12903-025-06496-z.
5
Pit and fissure sealants versus fluoride varnishes for preventing dental decay in the permanent teeth of children and adolescents.窝沟封闭剂与氟化物漆预防儿童和青少年恒牙龋齿的比较
Cochrane Database Syst Rev. 2016 Jan 18;2016(1):CD003067. doi: 10.1002/14651858.CD003067.pub4.
6
Effectiveness of silver diamine fluoride in caries prevention and arrest: a systematic literature review.氟化亚锡在龋齿预防和控制中的有效性:一项系统文献综述。
Gen Dent. 2017 May-Jun;65(3):22-29.
7
Antimicrobial effect of silver diamine fluoride (SDF) in arresting dentine caries of permanent teeth: A Systematic review.氟化亚锡(SDF)对恒牙牙本质龋的抗菌作用:一项系统评价。
F1000Res. 2024 Dec 6;13:1495. doi: 10.12688/f1000research.158864.1. eCollection 2024.
8
Slow-release fluoride devices for the control of dental decay.用于控制龋齿的缓释氟化物装置。
Cochrane Database Syst Rev. 2018 Mar 1;3(3):CD005101. doi: 10.1002/14651858.CD005101.pub4.
9
Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis.银氨氟化溶液(SDF)在抑制乳磨牙龋损进展中的疗效:系统评价和荟萃分析。
Int J Environ Res Public Health. 2022 Oct 9;19(19):12917. doi: 10.3390/ijerph191912917.
10
Silver Diamine Fluoride vs Atraumatic Restoration for Managing Dental Caries in Schools: A Cluster Randomized Clinical Trial.氟化亚锡银与非创伤性修复在学校龋齿管理中的应用:一项整群随机临床试验
JAMA Netw Open. 2025 Jun 2;8(6):e2513826. doi: 10.1001/jamanetworkopen.2025.13826.

本文引用的文献

1
Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children: A Systematic Review.氟化亚锡在儿童龋齿防治中的临床试验:系统评价
JDR Clin Trans Res. 2016 Oct;1(3):201-210. doi: 10.1177/2380084416661474. Epub 2016 Aug 20.
2
Effectiveness of silver diamine fluoride in caries prevention and arrest: a systematic literature review.氟化亚锡在龋齿预防和控制中的有效性:一项系统文献综述。
Gen Dent. 2017 May-Jun;65(3):22-29.
3
Clinical Use of Silver Diamine Fluoride in Dental Treatment.氟化亚锡在牙科治疗中的临床应用。 (你提供的原文有误,原文是Silver Diamine Fluoride,正确译文应该是:氟化银氨在牙科治疗中的临床应用。 )
Compend Contin Educ Dent. 2016 Feb;37(2):93-8; quiz100.
4
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent.加州大学旧金山分校使用氟化亚锡铵进行龋齿抑制的方案:基本原理、适应症及同意书
J Calif Dent Assoc. 2016 Jan;44(1):16-28.
5
Minimal intervention dentistry for managing dental caries - a review: report of a FDI task group.微创牙科治疗龋病管理——综述:国际牙科联盟工作组的报告。
Int Dent J. 2012 Oct;62(5):223-43. doi: 10.1111/idj.12007.
6
Randomized clinical trial on effectiveness of silver diamine fluoride and glass ionomer in arresting dentine caries in preschool children.随机临床试验研究了氟化银氨和玻璃离子体在学龄前儿童龋齿中的应用效果。
J Dent. 2012 Nov;40(11):962-7. doi: 10.1016/j.jdent.2012.08.002. Epub 2012 Aug 11.
7
Efficacy of silver diamine fluoride for Arresting Caries Treatment.氟化氨银用于龋齿治疗的疗效。
J Dent Res. 2009 Jul;88(7):644-7. doi: 10.1177/0022034509338671.
8
Promoting caries arrest in children with silver diamine fluoride: a review.用氟化亚锡促进儿童龋齿停止进展:综述
Oral Health Prev Dent. 2008;6(4):315-21.

氟化亚锡对成年患者龋齿的防治效果。

Effectiveness of Silver Diamine Fluoride in Arresting Caries in Adult Patients.

作者信息

Rashid Mohammed E

机构信息

Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Taibah University, Al Madinah Al Munawara, Kingdom of Saudi Arabia.

出版信息

J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1288-S1290. doi: 10.4103/jpbs.jpbs_240_25. Epub 2025 Jun 18.

DOI:10.4103/jpbs.jpbs_240_25
PMID:40655795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12244883/
Abstract

BACKGROUND

Silver diamine fluoride (SDF) has emerged as an effective, noninvasive treatment for arresting dental caries. While its use has been extensively studied in pediatric populations, there is limited evidence regarding its effectiveness in adults.

MATERIALS AND METHODS

This prospective study was conducted on 100 adult patients aged 25-60 years with active caries lesions in posterior teeth. Participants were randomly divided into two groups: the experimental group received a single application of 38% SDF, while the control group received standard fluoride varnish. Caries arrest was assessed using visual-tactile examination and scored using the International Caries Detection and Assessment System criteria at baseline, 1 month, and 6 months. Patient satisfaction and side effects were also documented. Statistical analysis was performed using paired -tests and Chi-square tests, with a significance level set at < 0.05.

RESULTS

After 6 months, 85% of caries lesions in the SDF group were arrested, compared to 45% in the fluoride varnish group ( < 0.001). Patient satisfaction scores were significantly higher in the SDF group, with a mean score of 4.7 compared to 3.5 in the control group. Minor side effects, such as temporary staining, were observed in 90% of SDF-treated teeth but were deemed acceptable by patients.

CONCLUSION

The application of 38% SDF is highly effective in arresting caries in adult patients and provides a promising, minimally invasive treatment option. Although tooth staining remains a common side effect, its clinical benefits outweigh aesthetic concerns, making it a valuable tool in caries management.

摘要

背景

氟化亚锡已成为一种有效的龋齿非侵入性治疗方法。虽然其在儿科人群中的应用已得到广泛研究,但关于其在成人中的有效性的证据有限。

材料与方法

本前瞻性研究对100名年龄在25至60岁之间的后牙患有活动性龋损的成年患者进行。参与者被随机分为两组:实验组接受一次38%的氟化亚锡治疗,而对照组接受标准氟化物漆治疗。在基线、1个月和6个月时,使用视觉触觉检查评估龋齿进展情况,并根据国际龋齿检测和评估系统标准进行评分。还记录了患者满意度和副作用。使用配对t检验和卡方检验进行统计分析,显著性水平设定为<0.05。

结果

6个月后,氟化亚锡组85%的龋损得到控制,而氟化物漆组为45%(<0.001)。氟化亚锡组患者满意度得分显著更高,平均得分为4.7,而对照组为3.5。在90%接受氟化亚锡治疗的牙齿中观察到轻微副作用,如暂时染色,但患者认为可以接受。

结论

应用38%的氟化亚锡对成年患者的龋齿控制非常有效,并提供了一种有前景的微创治疗选择。虽然牙齿染色仍然是常见的副作用,但其临床益处超过了美观问题,使其成为龋齿管理中的一种有价值的工具。