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Silver in health care: antimicrobial effects and safety in use.医疗保健中的银:抗菌作用及使用安全性
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用于减轻交叉感染风险的牙周探针抗菌涂层的设计与评估

Design and Evaluation of Antimicrobial Coatings on Periodontal Probes to Mitigate Cross-Infection Risks.

作者信息

Choudhary Anushree, Benjamin Niharika, Sushma Bedkekar, Saggar Sheewali, Hari Krishnan, Moothedath Muhamood

机构信息

Department of Periodontology, Hitkarini Dental College and Hospital, Jabalpur, Madhya Pradesh, India.

Department of Public Health Dentistry, Government Dental College and Hospital, Jamnagar Gujarat, India.

出版信息

J Pharm Bioallied Sci. 2025 Jun;17(Suppl 2):S1538-S1540. doi: 10.4103/jpbs.jpbs_100_25. Epub 2025 Jun 18.

DOI:10.4103/jpbs.jpbs_100_25
PMID:40655841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12244739/
Abstract

BACKGROUND

Periodontal probes are essential tools in dental diagnostics, yet they pose a significant risk for cross-infection if not adequately sterilized. The development of antimicrobial coatings offers a promising approach to reduce microbial contamination on these instruments, thereby enhancing infection control measures.

MATERIALS AND METHODS

This study aimed to design and evaluate the efficacy of antimicrobial coatings applied to periodontal probes. A total of 50 stainless steel probes were divided into two groups: Group A (uncoated probes) and Group B (probes coated with a silver nanoparticle-based antimicrobial layer). The probes were subjected to microbial exposure using a standard inoculum containing and . Colony-forming units (CFUs) were quantified before and after exposure to the coatings. The durability of the coating was assessed by repeated sterilization cycles and mechanical abrasion tests.

RESULTS

The antimicrobial coating significantly reduced microbial load, with Group B showing a 95% reduction in CFUs compared to Group A ( < 0.01). The coated probes maintained their antimicrobial efficacy after 30 sterilization cycles and demonstrated minimal wear during abrasion tests. No adverse effects on the structural integrity of the probes were observed.

CONCLUSION

The application of antimicrobial coatings on periodontal probes is an effective strategy to reduce the risk of cross-infection. These coatings demonstrated robust antimicrobial properties and maintained durability under clinical conditions. Future research should explore the long-term clinical applicability and cost-effectiveness of this intervention.

摘要

背景

牙周探针是牙科诊断中的重要工具,但如果消毒不充分,它们会带来显著的交叉感染风险。抗菌涂层的开发为减少这些器械上的微生物污染提供了一种有前景的方法,从而加强感染控制措施。

材料与方法

本研究旨在设计并评估应用于牙周探针的抗菌涂层的效果。总共50根不锈钢探针被分为两组:A组(未涂层探针)和B组(涂有基于银纳米颗粒的抗菌层的探针)。使用含有 和 的标准接种物使探针暴露于微生物环境中。在暴露于涂层前后对菌落形成单位(CFU)进行定量。通过重复消毒循环和机械磨损试验评估涂层的耐久性。

结果

抗菌涂层显著降低了微生物负荷,B组与A组相比CFU减少了95%( < 0.01)。涂覆的探针在30次消毒循环后仍保持其抗菌效果,并且在磨损试验中显示出最小的磨损。未观察到对探针结构完整性的不利影响。

结论

在牙周探针上应用抗菌涂层是降低交叉感染风险的有效策略。这些涂层表现出强大的抗菌性能,并在临床条件下保持耐久性。未来的研究应探索这种干预措施的长期临床适用性和成本效益。